Director, Global Commercial Strategy – GI

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Marketing

Job Sub Function:

Strategic Marketing

Job Category:

Professional

All Job Posting Locations:

Horsham, Pennsylvania, United States of America, Spring House, Pennsylvania, United States of America

Job Description:

We are searching for the best talent for a Director, Global Commercial Strategy – GI located in Horsham, PA or Spring House, PA.

About Immunology

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

Purpose: The Director, Global Commercial Strategy – GI will drive integrated commercial strategy across early discovery through late-stage development assets within the GI portfolio. This role partners closely with GCSO, R&D, Medical Affairs, Market Access, Business Development, and regional commercial teams to embed commercial input early, shape development decisions, advance launch readiness, and maximize long-term asset and portfolio value. This position reports to Sophie Shen, Senior Director, Global Commercial Strategy – Gastroenterology (GI).

Key Responsibilities:

Early Development & Portfolio Strategy

• Serve as the commercial lead for early-stage Compound Development Teams (CDTs), embedding commercial strategy from discovery through proof-of-concept to ensure development plans are aligned with DAS roadmap and long-term portfolio value
• Translate the DAS roadmap into actionable asset-level strategies by defining priority disease spaces, patient segments, clinical value drivers, differentiation requirements, and evidence needs across the early pipeline
• Shape target product profiles (TPPs), indication sequencing, competitive positioning, and go/no-go criteria to support timely investment decisions and maximize probability of technical, regulatory, and commercial success
• Provide commercial input into clinical trial design, endpoint selection, comparator strategy, patient enrichment, line-of-therapy positioning, and label-enabling evidence generation for priority GI assets
• Drive portfolio prioritization across internal programs and external innovation opportunities, integrating unmet need, competitive intensity, mechanism differentiation, market access feasibility, and revenue potential
• Partner with Business Development, R&D, Medical Affairs, GCI, Market Access, and regions to evaluate external assets, combination strategies, and white-space opportunities that can accelerate or strengthen execution of the GI roadmap
• Develop executive-ready recommendations for governance forums, including CDT, DAS, IPC, and portfolio reviews

Late Development & Launch Preparation

• Partner with late-development program teams to translate asset strategy into launch-ready commercial plans, including indication prioritization, evidence gaps, competitive readiness, positioning, and value proposition
• Lead commercial workstreams for late-stage assets, ensuring the launch strategy is grounded with solid forecasting from regional input
• Shape pre-launch planning across target product profile refinement, launch sequencing,