Physician Scientist, Diseases of Aging and Regenerative Medicine (DARe)

Band

Level 6

 

Job Description Summary

Internal Title: Director

#LI-Hybrid

This position will be located in the US (Cambridge, MA or East Hanover, NJ) and will not have the ability to be located remotely.

About the role:

Novartis BioMedical Research (BR) is the innovation engine of Novartis that collaborates across the company and beyond, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Translational Medicine (TM) is the clinical research arm of
BR and includes about 900 associates globally. TM plays a pivotal role in bringing innovative medicines to patients, by building on research advances to develop new therapies, and bridging drug discovery and clinical application.

The TM Discovery & Profiling (TMDP) is a group of physicians and clinical researchers who drive innovative science from discovery to the patient through the selection, profiling, and effective development of medicines. Translational medicine experts oversee Phase 1 and 2 clinical trials to demonstrate early safety and efficacy, as well as support for Phase 3 development through clinical pharmacology profiling studies. Translational medicine experts are key and highly visible members of global cross-functional project teams that design and implement early research and discovery projects, that then culminate in clinical trails. Translational medicine experts collaborate with colleagues in biology and chemistry to identify targets in diseases with significant unmet medical needs and provide input on likely clinical development pathways. The studies led by our translational medicine experts are among the most critical steps in drug development at Novartis.

As a TM Expert for DARe, you will collaborate with the Disease Area Head to develop high value decision-strategies for the Translational Medicine component of drug development projects and lead global cross-functional project teams through early development and beyond.

 

Job Description

Key Responsibilities:

•    In collaboration with research scientists identify, develop and implement strategy for preclinical support of program related objectives; this includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications and other relevant activities

•    Lead global project teams through early phase development, participate in project teams through program life cycle 
•    Responsible for clinical portions of the Integrated Development Plan (IDP) through Transition Decision Point (TDP)
•    Acts as medical monitor for one or more clinical studies
•    Communicate clinical team matters to project teams and relevant decision boards (Disease Area Decision Board).
•    Convene relevant (internal and external) leaders to consider proposed approach to development.
•    Evaluate clinical centers and foster communication with crucial collaborating investigators
•    Oversee publication and external presentation of clinical study results
•    Accountable for compound related biomarker strategies; work closely with biomarker experts in implementation
•    Participate in team presentations to Health Authorities as TM Expert

Essential Requirements:

•    Doctoral degree, MD required with clinical subspecialty training preferred in one of the following areas: Neurology, Metabolism/Endocrinology or Gerontology; Additional PhD/post-doctoral equivalent research and/or board-certification in relevant sub-specialty area preferred.
•    5 plus years experience in a pharmaceutical/biotech company, CRO or academic medical center or related experience.
•    Recognized for medical expertise.
•    Recognized for scientific expertise: respected by colleagues internally and externally, have made significant contributions to the field and created / established new concepts; record of high quality
•    publications in international scientific journals.
•    Excellent written and oral communication/presentation skills.
•    Independence: Able to work independently on study planning and execution, and with supervision on project planning.
•    Leadership of Collaborations: Able to lead multidisciplinary teams in a matrix organization.
•    Innovation: Seeks out new clinical discovery opportunities and PoC approaches.
•    Additional consideration for candidates with advanced research experience in data science, genetics/genomics or digital electrocardiography.
•    Demonstrated passion for science.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between: $236,600 to $439,400/year;  however, while