Director, Clinical Outsourcing

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeting protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on delivering oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Kymera is also progressing degrader oncology programs that target undrugged or poorly drugged proteins to create new ways to fight cancer. Founded in 2016, Kymera has been recognized as one of Boston’s top places to work for the past several years. For more information about our science, pipeline, and people, please visit www.kymeratx.com.

 

How we work:

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

 

How you’ll contribute:

1. Devises and implements clinical outsourcing strategies
   • Translates Kymera’s strategy, evolving portfolio and financial value creation goals into a clinical outsourcing strategy that meets these requirements
   • Develops and formalizes partnerships with key clinical suppliers 
   • Leads/facilitates development of key clinical supplier selection strategies for individual programs, using outsourcing processes designed to deliver the highest value (performance/financial) and that drive cross functional endorsement
   • Represents Kymera in a way that attracts the best suppliers and the best people within those suppliers
   • Leads internal business case development in support of functional build
   • Liaises with the head of strategic sourcing to ensure that Kymera sourcing strategies are consistent and not conflicting across business areas.
2. Drives delivery and performance from Kymera’s clinical outsourcing suppliers and contracts through supplier relationship management and partnership building
   • Oversee and lead governance activities (i.e., Executive Oversight Committee and Joint Operating Committee) for key clinical suppliers
   • Clarifies performance expectations from both Kymera and the supplier
   • Identifies and maintains program outsourcing performance metrics/KPIs and uses effective, bi-directional feedback to drive continuous improvement of quality, cost and time 
3. Helps Kymera’s programs and functions capture full impact from clinical outsourcing
   • Maintains concise, user-friendly standard outsourcing processes that embed continuous learning across programs
   • Coach collaboration between Kymera and the suppliers
   • Provide input into planning of clinical programs through the use of supplier insights
   • Create channels for systematic capture of expertise from our suppliers on innovations in trial practices and Kymera’s therapeutic areas
4. In collaboration with Kymera Strategic Sourcing function, implements best practices for supplier qualification, contracting and financial management
   • Ensure end-to-end communication between QA, legal, procurement, and finance for effective vendor qualification, Master Clinical Service Agreement and Scope of Work development, and financial forecasting and reviews

 

Skills and experience you’ll bring:

• Bachelor’s degree in related field and 10+ years’ experience in Clinical Drug Development outsourcing
• A proven track record of creating clinical outsourcing strategies that deliver value
• Exceptional negotiation skills and a tenacious problem-solver with a focus on building mutually beneficial relationships
• In-depth understanding of industry standards and applicable guidelines; FDA regulations and ICH GCP knowledge
• Extensive experience managing CROs, vendors, budgets, and timelines
• Experience developing Clinical Operations metrics
• Proven leadership experience with the desire and ability to work in a fast-paced, matrixed, start-up environment
• Strong collaboration and team-working, communicat