Director/Sr. Director - Neuroscience Clinical Biomarker Science

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Sr. Director of Neuroscience Clinical Biomarker Science is a critical scientific leadership position, serving as a key expert in Neuroscience biomarkers for clinical trials, external development initiatives, and program execution. This role builds on Lilly’s strong legacy of Neuroscience biomarker innovation and plays a central part in advancing therapies to patients. The Sr. Director will have the opportunity to work with unique clinical trial datasets and help generate new data that will shape the future of patient care. 

Key Responsibilities: 

• Provide expert guidance on Neuroscience clinical biomarkers in Lilly clinical trials, supporting research teams on patient selection, target engagement, and pharmacodynamic biomarkers, as well as advising on novel biomarker development. 
• Deliver clinical program biomarker plans.
• Lead the execution of clinical biomarker programs. 
• Review Clinical and Biomarker Standard Operating Procedures. 
• Contribute to the design, drafting, and review of clinical protocols. 
• Act as a scientific liaison for Lilly with external partners, researchers, and consortia. 
• Support business development, clinical, and imaging teams on external collaborations, offering scientific expertise on the use of Lilly compounds in partner-led projects. 
• Provide input into scientific and regulatory strategies, compound selection, clinical development plans, and commercial strategies as needed.
• Represent Lilly in public scientific forums. 
• Perform additional duties as assigned. 

Contribute scientifically to: 

• Clinical Study Reports 
• Statistical Analysis Plans 
• Publications and presentations 
• Regulatory communications 

Basic Qualifications: 

• PhD in neuroscience or a closely related scientific field with a minimum of 5 years experience in clinical research 

Additional Skills/Preferences: 

• Strong background in biomarker research, ideally with expertise in both fluid and imaging biomarkers 
• Experience in the pharmaceutical industry is preferred; alternatively, a robust academic background with leadership experience in research 
• Proven analytical and problem-solving abilities 
• Strong communication, listening, writing, and interpersonal skills 
• Demonstrated learning agility, critical thinking, and negotiation skills 
• Effective delegation and leadership capabilities 

Additional Information: 

• Travel required: 5–15% (domestic and international) 

Join Us: 

If you’re passionate about scientific innovation and driven to improve patient lives through pioneering biomarker research, Lilly offers the platform, people, and purpose to turn your ambition into real-world impact. Let’s make life better—together. 

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VL