Process Development Senior Scientist - Drug Substance Technologies - Synthetics (DSTS)

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Senior Scientist - Drug Substance Technologies - Synthetics (DSTS)

What you will do

Let’s do this! Let’s change the world!

Amgen is currently seeking a talented Process Development Senior Scientist to join our Drug Substance Technologies - Synthetics (DSTS) group. Amgen’s DSTS group within Process Development (PD) is responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists within our team apply their synthetic training to invent synthetic routes and chemical processes to support drug substance manufacturing from early to late-stage development.

The successful candidate will be a highly motivated and team-oriented individual with a strong background in organic chemistry and/or biochemistry with a proven track record of scientific innovation and achievement.

Key Responsibilities:

• Invent synthetic routes and develop safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances

• Advance enabling technologies to accelerate pharmaceutical development and to improve sustainability and process efficiency

• Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers

• Ensure process performance through process understanding, modeling and characterization

• Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc.

• Work cross-functionally to deliver regulatory documents and support regulatory filings

• Serve as a technical expert and keep current in the field of organic and process chemistry

• Work effectively in a multi-disciplinary team of chemists, engineers and attribute scientists

• Work independently in advancing projects and studies within required deadlines.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a Scientist with these qualifications.

Basic Qualifications:

• Bachelor’s degree and 5 years of Scientific experience OR

• Master’s degree and 3 years of Scientific experience OR

• Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]

Preferred Qualifications:

• Ph.D. in organic chemistry and/or biochemistry with a specialization in total synthesis, reaction methodology, mechanistic studies, biocatalysis, peptide chemistry, oligonucleotide chemistry, conjugation chemistry and/or chemoinformatics/machine learning

• Post-doctoral experience in an academic laboratory or pharmaceutical/biotech industry

• Track record of peer-reviewed publications and research presentations

• Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results

• Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on complex projects

• A research summary included with CV is strongly encouraged

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in