Research Scientist, Molecular Biology

About GenScript

GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.

GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology.

About ProBio

ProBio proactively provides end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy, vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers. ProBio’s total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing. 

Position: Research Scientist, Molecular Biology

Location: Redmond (Seattle), WA

Reporting to: Project Lead

Role Description:

We are seeking a versatile Research Scientist with strong background in the areas of molecular biology product development focusing on synthetic biology. This Research Scientist will play multiple roles within the R&D group and work within a small team responsible for development of cutting-edge molecular biology products and technologies with an emphasis on building gene and DNA libraries using semiconductor powered synthetic DNA. 

Key Responsibilities:

• Design of molecular biology products and services with GenScript’s proprietary semiconductor based high-throughput DNA synthesis platform
• Innovate for the next generation gene synthesis technology with simplified process, enhanced quality and safety profile.
• Develop new products to expand service capability and scope, including but not limit to gene and library assembly technologies, and cell free DNA amplification and synthesis technologies.
• Participate in molecular biology and synthetic biology application development, e.g., reagents, gene synthesis, vector design/construction, expression, protein engineering, microbe strain engineering, etc.
• Assembly of gene fragment library with chip-based oligo pools.
• Quality assay development for synthetic DNA libraries
• Perform statistical data analysis and present the results.
• Write and review technical documents including SOPs, product analysis report, presentations, patents.
• Tech transfer for research project’s translation, collaborate with manufacturing team and quality team to ensure a successful product launch and continuous process improvement
• Support day-to-day operations, problem-solving and troubleshooting for production team.

Qualifications:

• Bachelor’s (BSc) or Master’s (MSc) degree in Biochemistry, Molecular Biology, Chemical Biology, Synthetic Biology, or a closely related discipline. Candidates with a BSc must have at least 3 years of hands-on molecular biology experience in related industries.
• Demonstrated track record in gene synthesis, DNA assembly, library construction or synthetic biology.
• Proficiency in molecular biology laboratory techniques, including: multiplex PCR, dPCR/qPCR, primer/probe/vector design, enzymatic reactions, and molecular cloning.
• Experience in the design and construction of genes, pathways, expression vectors.
• Preferred experiences: next generation sequencing (NGS) is preferred; and familiarity with laboratory automation systems and workflows.
• Proven ability to collaborate effectively within dynamic, fast-paced, and cross-functional matrix teams.
• Strong documentation skills, including preparation of data summaries, technical and scientific reports, and the ability to transfer procedures to manufacturing teams.
• Self-motivated, passionate about scientific discovery, and comfortable working in a fast-paced team environment.

Benefit:

• Medical Insurance/ Vision Insurance/ Dental Insurance
• 401(k) & Retirement Savings Plan (RSP)
• Short Term Disability Insurance
• New Child Leave
• Paid Time Off
• Paid Company Holidays per year
• Paid Sick Days (earned based on hours worked)
• Compassionate Leave
• Jury Duty Leave
• Float day
• Personal days

Perks: 

• Free colleague meals during shift