Supervisor, Manufacturing, Large Scale Plasmid

The Role
Moderna is seeking a Manufacturing Supervisor to lead a cohesive team manufacturing DNA Plasmid for mRNA vaccines and therapeutics at our GMP site in Norwood, MA. This night shift (Wednesday-Saturday) position supports both startup and ongoing operations.

As a hands-on front-line leader, you will oversee a high-performing, flexible team to deliver clinical and commercial-grade DNA Plasmid. You’ll apply bioprocess and cGMP knowledge, learn the Moderna platform, and ensure operational excellence with a focus on safety and product quality.

Here’s What You’ll Do

• Lead daily operations including aseptic processing, fermentations, lysis, purification, and equipment oversight in a GMP environment

• Coach and supervise staff with a strong floor presence; conduct training and batch record reviews to maintain compliance and readiness

• Ensure safety, quality, and operational excellence through audit support, deviation handling, and continuous improvement

• Drive team performance, development, and succession planning aligned with Moderna’s goals

• Utilize digital and manufacturing systems (e.g., SAP, VEEVA, Syncade, LIMS, CMMS) to support execution and data integrity

Here’s What You’ll Need (Basic Qualifications)

• STEM degree with 3-5 years’ experience, or Associates’ degree with 5-8 years, or HS Diploma with 8 years’ experience

Here’s What You’ll Bring to the Table (Preferred Qualifications)

• Prior team or project leadership experience

• Strong understanding of GMP regulations

• Skilled in manufacturing systems and digital tools

• Effective communicator and motivator

• Demonstrated ability to work in and foster a collaborative, inclusive culture

• This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.

At Moderna, we believe that when you feel your best, you can do your best work.  That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.

• Best-in-class healthcare coverage, plus a suite of voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Lifestyle Spending Accounts to personalize your well-being journey
• Family planning and adoption benefits
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investment opportunities
• Location-specific perks and extras

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.  

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. 

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. 

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. 

Our Working Model 

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. 

Moderna is a smoke-free, alcohol-free, and drug-free work environment. 

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, milita