Manager, Internal Audit

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

Summary

The Manager of Internal Audit will play a pivotal role in executing and enhancing the internal audit function, with a strong emphasis on Sarbanes-Oxley (SOX) compliance and operational audits. This individual will contribute to building a scalable and effective audit program, supporting risk management, control evaluation, and governance processes. The role will support the management of co-sourced resources, collaborating across departments, and delivering value-added insights to improve business processes and controls. Reporting to the Head of Internal Audit, this role requires close collaboration with finance, commercial, product, technology, lab operations, and other members of management to maintain transparency, integrity, and accountability within the organization.

This position will be hybrid in office two days per week in Stamford, CT and may require occasional travel (~20%).

Job Responsibilities

• Lead and manage key components of the SOX compliance program, including risk assessment, scoping, testing, and reporting in alignment with the annual audit plan.
• Conduct walkthroughs and review documentation of business processes, risks, control activities, and supporting technologies.
• Evaluate the design and operating effectiveness of internal controls through detailed workpaper reviews.
• Draft and communicate audit findings, ensuring timely and actionable feedback to stakeholders.
• Serve as a subject matter expert on SOX, risk assessments, and internal controls, providing guidance to business and risk partners.
• Assist in the Internal Audit Risk Assessment process, incorporating insights from company-wide risk assessments into planning and executing the planned audits and ad-hoc internal audit projects.
• Manage multiple concurrent workstreams, prioritize tasks, coordinate with external auditors, and oversee the workload of internal team members and co-sourced partners.
• Provide training and mentorship to audit staff and control owners on SOX requirements and industry best practices.
• Identify and recommend opportunities for process improvements and control enhancements.
• Support the growth and innovation of the internal audit function through recruiting, onboarding, and the adoption of emerging technologies.

Education, Experience, and Skills

• BS in Accounting, Finance, Economics, IT or other related field; advanced degree a plus.
• Certified Internal Auditor (CIA) or Certified Public Accountant (CPA) required.
• 7+ years of experience in auditing and/or compliance, including SOX program management.
• Experience managing co-sourced resources and leading audit teams.
• Strong understanding of internal control frameworks, financial reporting, enterprise risk frameworks.
• Familiarity with enterprise resource planning (ERP) systems, GRC platforms, and audit management software. Experience with NetSuite or Audit Board a plus.
• Experience within the Healthcare industry.
• Excellent project management, analytical, and communication skills.
• Ability to build relationships across all levels of the organization.
• High attention to detail and commitment to accuracy and transparency.
• Ability to work in a fast paced, action-oriented environment.

 

Pay Transparency, Budgeted Range$130,000—$150,000 USD

~

Science - Minded, Patient - Focused. 

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most. 

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.