Global Commercial Director, ImmunoOncology
AstraZenecaAbout the role
Location: Wilmington
Hybrid Policy: 3 days a week onsite
As Global Commercial Director, ImmunoOncology, this role shapes how ground-breaking oncology medicines reach patients worldwide. Working across a broad and innovative pipeline, the position blends commercial competence with scientific understanding to bring novel treatments to those who need them most. It leads the commercial strategy for key immuno-oncology disease areas, with a particular focus on the end-to-end launch and sustained performance of the MATTERHORN gastric cancer programme. Operating at the centre of cross-functional collaboration, this role drives focused execution, informed decision-making and ambitious, insight-led choices that influence outcomes for patients, markets and the business. Ready to challenge convention, test new ideas and guide a high-performing team to deliver impact at scale?
Accountabilities
Lead the creation, execution and continuous refinement of a long-term commercial vision and strategy for immuno-oncology disease area(s), ensuring robust lifecycle management from prelaunch through postlaunch.
Chair and direct the IO disease area(s) Global Brand Team (GBT), setting clear priorities, driving accountability and ensuring coordinated delivery across functions and phases of launch.
Hold global budget accountability for the disease area, including development of the annual operating plan, budget phasing, investment prioritisation
Own global commercial leadership of the MATTERHORN gastric cancer launch, ensuring launch excellence, sustained performance and delivery against strategic and financial objectives.
Lead all aspects of postlaunch performance by monitoring uptake, driven dynamics, access and executional efficiency, initiating data-driven course corrections and reallocating resources where needed.
Represent and articulate the commercial and marketing strategic vision for the disease area(s) within the Global Portfolio Team (GPT), influencing key decisions and trade-offs.
Partner closely with the Global Medicines Lead (GML) to align commercial and medical strategies, ensuring integrated planning and coordinated resource deployment.
Develop and implement commercial strategies that optimise revenue, volume, margin and access across geographies within agreed budget envelopes.
Engage regional and key market stakeholders to drive launch readiness, build capabilities and ensure effective deployment of global and local budgets.
Act as indication lead in senior forums, communicating commercial performance, financial outlooks and investment trade-offs to senior executives and governance committees.
Deliver Phase 3 and prelaunch marketing strategies that set up successful launches and maintain strong postlaunch momentum.
Collaborate with extended teams to develop and implement sustainable pricing and access strategies across multiple indications.
Lead the development and global implementation of brand strategy, positioning, launch plans, forecasts, critical metrics and ongoing financial and performance analytics for the disease area(s).
Essential Skills/Experience
Strong strategic thinking, judgment, and influencing skills to lead across regions and markets with clear financial accountability.
Demonstrated experience owning or leading significant global commercial budgets, including investment prioritization, phasing, and governance.
Confirmed ability to use performance and financial analytics to inform decision making and drive course corrections.
Bachelor’s degree required; preferably a business or scientific graduate degree with a business related postgraduate qualification. Postgraduate degree in biological, chemical, or pharmacological sciences strongly desired.
10+ years’ experience in the pharmaceutical industry, including at least 5 years in oncology/immuno-oncology marketing, strategy, or life sciences consulting.
Strong leadership capabilities to set direction, inspire commitment, balance short and longterm financial and strategic needs, and resolve complex issues.
Strong business acumen and complex problem solving skills.
Experience developing and delivering short and longterm strategic plans for oncology portfolios, including postlaunch performance and budget management.
The annual base pay for this position ranges from $231,988.80 - $347,983.20 USD Annual and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowl
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