Senior Scientist II, Biological Sciences

Job Description

We are seeking a highly motivated, creative, and collaborative Senior Scientist to join our Biological Sciences drug discovery group. This position will be responsible for designing, performing, coordinating, and interpreting structural biology, biochemical, biophysical, and cellular experiments for our drug discovery programs. This includes the development of relevant model systems for the identification, validation, and screening of compounds against novel therapeutic targets. The successful candidate will work independently, but also as an integral part of a larger team to achieve collective goals. The ideal candidate will have a deep understanding of biochemistry and structural biology and will apply this this to challenging ongoing and new drug discovery programs.

This position will report to a Senior Director, Biological Sciences, and work onsite at our research facility in Lawrence, Kansas.

What You’ll Do:

• Conceive, develop, and optimize biochemical, biophysical, and cellular assays to determine the therapeutic potential of rationally designed targeted small molecules
• Work collaboratively with biologists, medicinal chemists, and external partners to deliver high quality structures of macromolecular complexes, custom proteins, and reagents
• Design and conduct rigorous experiments to identify and validate potential novel drug targets
• Document experimental design, analysis, and interpretation of data in an ELN and LIMS system
• Stay abreast of the latest scientific and technological advancements in the field
• Author technical reports and presentations to communicate data and analyses effectively
• Add to Deciphera culture of collaboration and shared mission to solve complex biological problems
• Adhere to corporate policies including safety and compliance

Qualifications

What You'll Bring:

• A PhD in Biochemistry or related field with 5+ years of biotech or pharma industry experience
• An ability to think independently to design high-throughput experiments and generate robust, reproducible results
• Experience working with automated laboratory instruments including ECHO, Bravo, and multi-mode plate readers
• Expertise in biochemistry, HTS assay development, molecular biology, protein purification, X-ray crystallography or Cryo EM. Familiarity with biophysical techniques such as protein MS, SPR, ITC, MST, DSF is preferred
• Adaptability to work in a dynamic, fast-paced environment
• Excellent communication and presentation skills

Additional Information

Benefits:

• Competitive salary and annual bonus.
• Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
• Generous parental leave and family planning benefits.
• Outstanding culture and opportunities for personal and professional growth.

Apply Now: Join us in our mission to improve the lives of people with cancer. Apply today to become a part of our dynamic team!

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements and to learn more about how we can increase diversity in our candidate pool, we invite you to voluntarily provide demographic information in a confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially.  Our commitment to increasing diversity in our candidate pool does not affect our commitment to equal employment opportunity, including our ongoing commitment to make all hiring and other employment decisions solely on a nondiscriminatory basis.