Scientist – Laboratory Operations and Automation

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities, and robust scientific methodology we collaborate to discover the next medical breakthrough.

The Cell Pharmacology group in Department of Quantitative Biosciences is seeking a highly motivated Scientist with a background in cell-based assays, automation and data deconstruction to join our company's Research Laboratories in Boston.  The primary responsibility of the successful candidate is to integrate with screening logistics, facilitate ROP execution and be part of 360° analyses of the data with software tools.  This integrated approach will improve workflow logistics, assay execution, data analyses and visualization with efficiency. 

Responsibilities:

• Interface compound workflow logistics and automation for weekly screening with knowledge in MOSAIC and writing protocols for Echo, Bravo, Hamilton and other automation instruments.

• Assay execution with engineered and primary cells for screening.

• Evaluate the pharmacology of novel small molecules, antibodies, and other modalities for therapeutic potential in immunology and oncology with fit-for-purpose automation in smoothening the workflow.

• Data analyses, curve fit and extended pharmacological assessment with Graphpad Prism, Excel and Spotfire.

• Manage large data sets in conjunction with in-house data base.

• Work across the organization to harmonize and innovate lab automation and data computing.

• Function and communicate effectively in a highly productive and multi-disciplinary environment.

Education Requirements:

• B.S./B.A. degree with a minimum 3 years of hands-on experience; or a M.S. degree with a minimum 1 year of hands-on experience.

Required Experience:

• Candidate should be a strong team player with wet lab and data analytics experience.

• Fundamental cell biology, protein, and molecular biology techniques.

• Knowledge of programming and maintenance of lab automation and plate readers.

• Excellent oral and written communication skills.

Desirable Experience:

• Knowledge of MATLAB, R or Python and SQL is desirable.

• Tibco Spotfire (dashboard, visualization & report development) with solid foundation in data management and data governance

• Experience in developing business relevant analyses and reports.

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NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders).  Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discret