Senior Product Manager, ECD

POSITION SUMMARY: 

We are seeking a Senior Product Manager to drive the development and lifecycle management of innovative products for early cancer detection (ECD). This individual will play a pivotal role in shaping and executing the product strategy for high-impact diagnostics aimed at improving patient outcomes through earlier interventions. With a deep understanding of product development in the diagnostics space, the ideal candidate will lead cross-functional teams through all phases of product development—from feasibility through launch, growth, and obsolescence.

This is a high-ownership role combining strategic vision and technical execution, requiring experience in the diagnostics or life sciences industry with a demonstrated ability to launch novel, clinically impactful products.

PRIMARY RESPONSIBILITIES: 

• Lead the product lifecycle for ECD diagnostics, from concept to commercialization, including product definition, planning, and delivery
• Define and execute a strategic product roadmap aligned with clinical and market needs for early cancer detection
• Translate complex clinical and scientific insights into clear product requirements in partnership with R&D, clinical affairs, software engineering, and regulatory teams
• Lead Voice of Customer (VOC) initiatives, competitive analysis, and market research to ensure product differentiation and customer satisfaction
• Define and monitor key product performance indicators (KPIs) such as sensitivity, specificity, and turnaround time; collaborate with cross-functional teams to drive continuous improvement
• Own product development documentation, including user needs, product requirements, and risk assessments
• Collaborate with Clinical and Regulatory Affairs to support study design, data analysis, and regulatory submissions
• Partner with Marketing and Commercial teams to establish value propositions, go-to-market strategy, pricing models, and launch readiness
• Develop financial models and business cases to support portfolio investment decisions and growth opportunities
• Provide regular updates to senior leadership and stakeholders on product development progress, roadmap evolution, and strategic priorities

QUALIFICATIONS: 

• Bachelor’s degree in a life science, engineering, or relevant technical discipline required; Master’s or advanced degree preferred
• Minimum 5+ years of experience in product management or development within the diagnostics, oncology, or medical device industries
• Deep understanding of early cancer detection technologies and clinical workflows strongly preferred
• Experience with regulated products, including IVDs or LDTs, and familiarity with FDA or CLIA regulatory pathways
• Proven ability to manage complex, cross-functional product development efforts in a matrixed environment

KNOWLEDGE, SKILLS, AND ABILITIES: 

• Strategic thinker with strong executional focus and a track record of delivering impactful products
• Exceptional ability to communicate scientific and technical information to both technical and non-technical audiences
• Strong project and process management skills; detail-oriented with excellent organizational capabilities
• Financial acumen for developing business cases and modeling product economics.
• Skilled in Microsoft Office and product management tools; experience with Agile development methodologies is a plus 
• Able to influence and align stakeholders across functions, from R&D to commercial

 

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$132,100—$165,100 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of gen