Senior Scientist- Surface Biology Early Validation

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Scientist – Surface Biology Early Validation

What you will do

Let’s do this. Let’s change the world. We are seeking an experienced Senior Scientist to support early validation of membrane protein targets through development and application of quantitative, cell-based assays.  

In this role, you will contribute to building and executing scalable experimental workflows that generate high-quality data on target expression, localization, and behavior in cellular systems. You will work closely with cross-functional partners to support discovery efforts across Therapeutic Areas.

• Design and execute scalable cell-based assays to assess membrane protein expression, localization, and internalization
• Apply flow cytometry-based approaches to generate quantitative and reproducible data
• Integrate complementary approaches such as imaging-based assays to support target evaluation
• Develop and optimize assays for robustness, scalability and consistency
• Analyze and interpret experimental data to support target evaluation
• Collaborate with cross-functional teams to integrate findings into discovery programs
• Maintain high standards of experimental rigor and documentation

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Professional we seek is a Senior Scientist with these qualifications.

Basic Qualifications:

• Doctorate degree OR
• Master’s degree and 2 years of scientific experience OR
• Bachelor’s degree and 4 years scientific experience OR
• Associate’s degree and 8 years scientific experience OR
• High school diploma / GED and 10 years scientific experience

Preferred Qualifications:

• PhD in Cell Biology, Molecular Biology, or related discipline
• 2+ years of relevant industry experience, including leadership of scientific projects or teams
• Strong expertise in flow cytometry, imaging, and cellular assay development
• Experience working with membrane proteins or receptor biology
• Experience with scalable or high-throughput assays workflows
• Familiarity with molecular biology techniques or genome editing approaches to support assay design
• Strong data analysis, troubleshooting, and problem-solving skills
• Effective collaboration and communication skills

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term