Principal Scientist I, Biotherapeutics Discovery

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram,��YouTube, LinkedIn and Tik Tok.

Job Description

Discovery Biotherapeutics and Genetic Medicine (BGM) at Abbvie is seeking a highly motivated Principal Scientist to join the Cell and Functional Biology group at the Cambridge Research Center (CRC) site based in Cambridge, MA.  This role will be responsible for the design and empowerment of screening strategies employed to advance promising biotherapeutics from early exploration through lead identification and optimization.  Close partnerships with Neuroscience and Immunology will be required to drive transformative ideas to the clinic. The ideal candidate should possess experience in large molecule screening strategy design including vitro cell-based assays, with a strong understanding of high-throughput screening, external research partner (CRO) capabilities, and brain shuttle systems highly valued.

Job Responsibilities:

• Develop in vitro functional assays leveraging diverse signaling pathways to transition early therapeutic ideas into enabled biotherapeutics campaigns.
• Design and employ strategic screening funnels for biotherapeutic discovery campaigns within the immunology and neuroscience therapeutic areas.
• Identify and integrate cutting-edge technologies and methodologies into screening and assay development, anticipating future trends in drug discovery.
• Conduct detailed analysis of complex data sets to extract key insights and guide decision-making processes in research projects.
• Foster strong cross-functional collaborations with therapeutic area partners to promote the generation of innovative ideas and solutions that support organizational objectives.
• Present and explain research findings and strategies clearly and effectively, preparing scientific r