Principal Research Scientist I, Peptide Medicinal Chemist

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

Small Molecular Therapeutics and Platform Technologies (SMTPT) within Discovery Research seeks an accomplished scientist to lead a team of medicinal chemists within the Global Medicinal Chemistry (GMEC) organization.  GMEC is committed to delivering first and best-in-class small molecules in conventional and unconventional drug-like space with the potential to improve human health.  The Principal Research Scientist I/Senior Scientist II will lead a team of chemists designing and synthesizing peptides (or other small molecule modalities) aimed at identifying and advancing promising low dose leads (responsibility for lead generation through candidate nomination).

She/He/They will be responsible for managing a diverse team of scientists who design and synthesize peptide drug candidates for novel targets throughout AbbVie’s drug discovery pipeline.  She/He/They may serve as Chemistry Lead for some of these efforts. She/He/They will also be a strong synthetic chemist who has demonstrated high productivity in synthesizing complex organic molecules including peptides. She/He/They and team will develop novel medicinal chemistry strategies and execute multiparametric optimization(s) of drug candidate properties in a highly collaborative environment aimed at accelerating the delivery of a sustainable pipeline of first in class/breakthrough peptide drug candidates with transformative potential.

The candidate will have experience with strategic planning, and leadership of medicinal chemistry teams as well as working with cross-functional and matrixed teams within the AbbVie therapeutic areas.  The candidate will have a strong expertise in modern medicinal chemistry, including an appreciation of modern computational and experimental