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Associate Director/Director, Head of Discovery Analytical Chemistry
IDEAYA BiosciencesSouth San Francisco, United Statesfull_timeVerifiedPosted 15 Dec 2024
About the role
IDEAYA Biosciences (NASDAQ: IDYA) is a public, clinical-stage precision medicine oncology company committed to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics. Our approach integrates extensive capabilities in identifying and validating translational biomarkers with small molecule drug discovery to select patient populations most likely to benefit from the therapies we are developing. We are applying these capabilities across multiple classes of precision medicine, including direct targeting of oncogenic pathways and synthetic lethality – which represents an emerging class of precision medicine targets. We believe this diversified approach will enable us to deliver the right medicine to the right patient to drive a more robust clinical response. IDEAYA has an industry leading platform and pipeline in precision medicine / synthetic lethality. IDEAYA wholly-owns or controls its three most-advanced clinical programs. It has established strategic collaborations with GSK, Amgen, Pfizer and Gilead supporting certain clinical and preclinical pipeline programs. When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use team work to move science forward. For more information, please see www.ideayabio.com.
Notice to Agencies and Recruiters: All open positions and candidate activity are strictly managed through Human Resources. Please note that our policy is that recruiters do not contact employees/hiring managers directly to solicit business and/or present candidates. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Please note that failure to comply with this request will be a factor in developing a professional relationship with IDEAYA Bio. Inquiries regarding developing a recruiting relationship with us, may be directed to HR@ideayabio.com
Position Summary:We are seeking an experienced and highly motivated Associate Director / Director, Analytical Chemistry to join our multidisciplinary team based in South San Francisco. The role requires the candidate to work collaboratively with the related cross-functional teams to support our drug discovery pipeline. The successful candidate will be responsible for but not limited to those listed below.This position is based in our South San Francisco headquarter offices and required to be onsite four days per week per our company policy.
Notice to Agencies and Recruiters: All open positions and candidate activity are strictly managed through Human Resources. Please note that our policy is that recruiters do not contact employees/hiring managers directly to solicit business and/or present candidates. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Please note that failure to comply with this request will be a factor in developing a professional relationship with IDEAYA Bio. Inquiries regarding developing a recruiting relationship with us, may be directed to HR@ideayabio.com
Position Summary:We are seeking an experienced and highly motivated Associate Director / Director, Analytical Chemistry to join our multidisciplinary team based in South San Francisco. The role requires the candidate to work collaboratively with the related cross-functional teams to support our drug discovery pipeline. The successful candidate will be responsible for but not limited to those listed below.This position is based in our South San Francisco headquarter offices and required to be onsite four days per week per our company policy.
What you'll do:
- Lead the analytical chemistry efforts in facilitating internal drug discovery by managing and executing compound purification (including chiral separations), structural elucidation, biophysical property determinations (such as solubility, logD, and pKa determinations), and stability studies
- Manage Discovery Analytical group to achieve high productivity with high quality and high scientific rigor
- Troubleshoot methods and provide technical guidance across discovery programs
- Manage installation and maintenance of lab analytical equipment.
- Train and supervise research associate and scientists to ensure proper execution of analytical experiments
- Perform vendor review and selection and provide oversight of all external analytical work
- Ensure analytical method qualification/validation/technical-transfer documentation (test protocols, methods, and reports) are relevant, accurate, and complete
- Stay aware of newly emerging techniques and technologies and bring new capabilities online as necessary
- Proactively communicate with and work closely with other functions to align analytical strategy to achieve goals
- Hire high-caliber analytical chemists to build and grow a world-class analytical department
- Craft and manage budgets
Requirements:
- Ph.D. in analytical chemistry or related discipline with minimum of (10) years of drug discovery/development experiences and demonstrated ability in leading cross-functional groups
- Strong subject matter expertise in small molecule purification, structural elucidation, multidisciplinary chemical analysis, analytical method development/validation, and CRO management
- Exceptional problem-solving skills and ability to quickly adapt and shift focus as needed
- Excellent interpe
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