Scheduled Hours

40

Position Summary

Dr. Miranda Orr is seeking an experienced and highly motivated Senior Research Lab Manager to oversee the scientific operations of the Bruker Spatial Biology Center of Excellence within their laboratory. The Orr Lab utilizes cutting-edge spatial biology platforms to investigate the cellular and molecular mechanisms underlying brain aging and neurodegenerative diseases. This position offers a unique opportunity to provide operational leadership, manage high-throughput spatial workflows, coordinate interdisciplinary research initiatives, and contribute to the advancement of novel technologies. The Senior Research Lab Manager will work closely with Dr. Orr and play a key role in driving the lab’s scientific mission while ensuring adherence to institutional policies and research best practices.

Manages the overall laboratory and operating function to ensure the safe and highly effective operation of research in compliance with regulatory requirements and interaction with other laboratories, vendors and/or participants. Performs, oversees and coordinates complex research projects.

Job Description

Primary Duties & Responsibilities:

• Oversee day-to-day operations of the Orr Lab and their associated Bruker Spatial Biology Center of Excellence.

• Manage and maintain a suite of cutting-edge instrumentation, including Bruker CosMx SMI, CellScape, and GeoMx DSP platforms.

• Manage the recharge center associated with the center of excellence and these instruments including rate setting, invoicing and quote generation.

• Develop and implement protocols for spatial transcriptomics and proteomics workflows; train lab members and collaborators.

• Coordinate research projects and collaborations involving the COE; serve as the primary technical and logistical point of contact.

• Coordinate, facilitate, and implement interdisciplinary collaborations across university departments, schools, and external partners to advance research in brain aging.

• Liaise with SILQ Center leadership and staff to support planning and reporting of progress.

• Ensure compliance with institutional safety standards and regulatory requirements.

• Monitor budgets, manage reagent and supply inventory, and assist with procurement and vendor relationships.

• Support data management and analysis pipelines in collaboration with bioinformatics teams.

• Contribute to manuscript and grant preparation by providing figures, methods, and technical expertise.

• Mentor junior lab members and promote a collaborative, high-performance lab culture.

Working Conditions:
Job Location/Working Conditions

• Works in a laboratory environment with potential exposure to biological and chemical hazards.

• Must be physically able to wear protective equipment and to provide standard care to research animals.

• Requires extensive safety training.

• Alternative work schedules.

Physical Effort

• Typically sitting at desk or table.

• Repetitive wrist, hand, or finger movement (PC Typing).

Equipment

• Office equipment.

• Lab/research equipment.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education:

Master’s degree or combination of education and/or experience may substitute for minimum education.

Certifications:

No specific certification is required for this position.

Work Experience:

Research Laboratory Operations (8 Years)

Skills:

Not Applicable

Driver's License:

A driver's license is not required for this position.

More About This Job

WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.

Preferred Qualifications

Education:

No additional education beyond what is stated in the Required Qualifications section.

Certifications:

No additional certification beyond what is stated in the Required Qualifications section.

Work Experience:

No additional work experience beyond what is stated in the Required