Senior Director, Pathology

At Kailera, we are bold, authentic and committed to our mission of developing therapies that give people the power to transform their lives and elevate their overall health. Rooted in an entrepreneurial spirit and a team-oriented culture, we are working together to advance Kailera’s mission to advance novel therapies for obesity and related conditions.
 
We are passionate about creating an inclusive workplace that promotes collaboration, integrity, and excellence. As we expand, we seek the most talented individuals with diverse backgrounds, cultures, perspectives, and experiences to join our team.

What You’ll Do:

The candidate will be responsible for pathology assessment of multiple pipeline candidates in Kailera’s portfolio. This will include primary evaluation and peer review of histopathology specimens, clinical pathology, and associated data from toxicology studies. The candidate will integrate the data and author relevant sections of regulatory documentation, study reports and manuscripts. The candidate will also review scientific literature to prepare risk assessment documents for inclusion in regulatory and scientific documents such as pediatric development plans, carcinogenicity waivers, and target risk assessments. This will include development of mechanistic understanding of on and off target toxicology findings. You will represent the company at meetings with regulators and at conferences. The candidate is expected to be a key member of multidisciplinary project teams, ensuring safe and effective use of therapeutics in clinical trials and beyond.

 

Responsibilities:

• Design, oversee, peer review and integrate pathology data from multiple toxicology studies
• Lead risk assessment of any findings in the context of clinical trials, in particular assessment of biological mechanisms of toxicity and comparison with other agents of the same class
• Author relevant sections of scientific and regulatory documents to an excellent standard to ensure seamless approval of relevant clinical trials
• Develop a deep understanding of relevant biology to enable scientific risk assessments and submission of regulatory documents such as carcinogenicity waivers and pediatric development plans
• Represent the department on multidisciplinary project teams such that drug candidates are developed rapidly and efficiently
• Provide advice and support to departmental senior leadership and be a visible advocate for the department across the company

 

Required Qualifications:

• At least 10 years of experience in drug development within industry
• Demonstrated excellence in evaluating anatomic pathology findings in multiple study types and species
• Demonstrated excellence in communication (written and oral)
• Ability and desire to take on leadership roles within the department and cross functionally
• Strong decision-making, complex problem solving, critical data analysis and interpretation.
• Demonstrated excellence working as a project team representative, driving forward drug development in a cross functional environment
• Ability to thrive in a fast-paced environment and comfort with ambiguity

 

Preferred Qualifications:

• Experience in developing drugs in the cardiometabolic field – particularly incretin therapies

 

Education:

• PhD in a related field
• DVM (or equivalent)
• Board certified by the American College of Veterinary Pathologists (ACVP), European College of Veterinary Pathology (ECVP) and/or Japanese College of Veterinary Pathology (JCVP)

Benefits of Working at Kailera

In addition to traditional benefits, we provide enhanced offerings designed to support the well-being and financial security of our team members and their families.

• Comprehensive health benefits and tax-advantaged savings accounts
• Flexible time off, 13 paid holidays, and a companywide year-end shutdown
• Monthly wellness stipend
• Generous 401(k) match
• Disability and life insurance

At Kailera, we are committed to fostering an inclusive culture. How we treat our people is reflective of this commitment. We share the pay range for this particular role with the actual base salary depending upon factors such as job-related knowledge, skills, market factors, and experience.

Salary Range$210,000—$270,000 USD

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION: 

Kailera Therapeutics, Inc. is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race (including traits historically associated with race,