Purification Process Development Engineer

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

• Supports non-GMP planning and execution of pipeline products in the R&D Pilot Plant (interface between lab-scale studies and full-scale GMP manufacturing, operating at the 50-1000L bioreactor scale). Work includes new product development, material supply needs, and demonstration runs for multiple programs spanning all phases of biopharmaceutical development
• Supports large scale downstream (purification) operations (70%) and upstream (cell culture) operations (30%) in a lab-based role.
  • Downstream activities include chromatography, ultrafiltration/diafiltration, and/or depth/sterile filtration. Planning includes transfer of long lead items, batch record/SOP development, sample plan building, ordering and vendor management, etc.
  • Upstream activities include vial thaw, cell culture expansion, large scale bioreactor setup and control, centrifugation
• Record, trend, and interpret data independently, and organize and present issues and results at departmental and project meetings
• Participate and interact with Process Development to identify and troubleshoot problems, support large scale studies, and support project goals.
• Requires accountability and consistent follow through on work assignments and personal objectives to deliver high quality results despite obstacles
• Occasionally, may work an adjusted schedule to meet operational demands

Qualifications

• BS in chemical engineering, biotechnology, chemistry, biology, pharmacy, engineering or related pharmaceutical science + 3 - 4 years relevant industry experience or MS in same + 1 - 2 years of experience
• Excellent documentation and communication skills
• Time management skills, effectively managing multiple priorities and outcomes of critical tasks
• Proficient in use of applicable lab equipment and operations and have an ability to independently interpret data, maintain an organized lab area and thrive in a fast-paced team environment
• Experience troubleshooting of activities routinely performed in downstream processing (i.e. traditional and continuous chromatography, UF/DF, filtration, column packing, and buffer preparation) or upstream processing is a plus
• Practical experience around scale-up, technology transfer, and manufacturing support of large scale GMP operations is desired. Knowledge of upstream processing is a plus
• Ability to wear personal protective equipment such as safety glasses/goggles, gloves,  shoes
• Must be proficient in Outlook, Microsoft platforms, and other general computer software and know-how is required.
• Ability to lift, pull, or push equipment requiring up to 75 lbs of force, stand for 6 hours in a suite, climb ladders and work platforms, stoop or bend to check or troubleshoot equipment operations

Additional Information

Position is full-time, Monday - Friday 8:00am - 5:00pm. Candidates currently living within a commutable distance of Lexington, MA are encouraged to apply. Excellent full-time benefits including comprehensive medical coverage, dental, and vision options.

• Excellent full-time benefits including comprehensive medical coverag