Medical Director, Enfortumab Vedotin

ROLE SUMMARY

The Medical Director will serve as a physician within the Enfortumab vedotin Oncology Late Development team, contributing to the development and execution of clinical strategies that advance transformative therapies for patients with cancer.

This role combines study-level clinical leadership with broader strategic contributions across the asset lifecycle. Working in close partnership with Clinical Scientists, Worldwide Medical, Translational Oncology, Biostatistics, Safety, Regulatory, and other cross-functional stakeholders, the Medical Director will help generate evidence that addresses both regulatory requirements and the evolving needs of patients, healthcare providers, and healthcare systems.

The successful candidate will bring strong scientific and clinical judgment, an interest in strategic drug development, and a collaborative mindset. This individual will be expected to leverage emerging technologies, including AI-enabled tools and advanced analytics, to enhance decision-making, accelerate insights generation, and improve operational efficiency.

ROLE RESPONSIBILITIES

Clinical Development Leadership

• Provide clinical leadership for clinical study teams, ensuring scientific rigor, patient focus, and alignment with program objectives.
• Partner closely with Clinical Scientists and cross-functional colleagues to deliver high-quality study execution and data generation.
• Conduct medical monitoring activities, including eligibility review, safety surveillance, data review, and clinical issue management.
• Lead peer-to-peer scientific engagement with investigators and key external experts.
• Serve as the clinical point of contact for investigators, ethics committees, steering committees, and regulatory authorities.
• Contribute to the design, development, and maintenance of clinical protocols, amendments, clinical study reports, investigator materials, and regulatory documentation.

Strategic Development & Evidence Generation

• Contribute to the development of clinical and evidence-generation strategies that support both regulatory objectives and broader patient and healthcare stakeholder needs.
• Apply evolving understanding of the oncology landscape, standard of care, and competitive environment to inform development decisions and study planning.
• Collaborate with Worldwide Medical and cross-functional partners to ensure alignment of evidence generation priorities throughout the product lifecycle.
• Support identification of opportunities to optimize development programs through innovative trial design, external insights, and emerging scientific advancements.

Data Interpretation & Insight Generation

• Partner with Clinical Scientists and quantitative functions to review, interpret, and communicate clinical data and emerging evidence.
• Translate complex clinical findings into actionable insights that guide program-level decisions and future development plans.
• Utilize advanced analytics and AI-enabled tools to enhance data synthesis, knowledge generation, and operational efficiency.
• Contribute to scientific communications, publications, congress presentations, and internal governance discussions as appropriate.

Collaboration & External Engagement

• Foster strong partnerships across Clinical Development, Worldwide Medical, Safety, Regulatory, Biometrics, Translational Sciences, and Commercial colleagues as appropriate.
• Maintain awareness of emerging scientific, clinical, and healthcare trends relevant to the therapeutic area.
• Engage with external experts, investigators, and scientific communities to gather insights that inform development strategy.
• Promote a culture of innovation, continuous learning, and patient-centered drug development.

BASIC QUALIFICATIONS

• MD, DO, or equivalent medical degree.
• 2-5 years of pharmaceutical, biotechnology, academic research, or clinical development experience.
• Demonstrated understanding of clinical research methodology and drug development.
• Strong scientific communication and cross-functional collaboration skills.

PREFERRED QUALIFICATIONS

• Board certified or board eligible in Oncology, Hematology/Oncology, or related specialty.
• Experience supporting oncology clinical trials.
• Understanding of late-stage clinical development, evidence generation, and the oncology treatment landscape.
• Ability to interpret complex clinical data and translate findings into strategic insights.
• Experience utilizing digital, analytical, or AI-enabled tools to support decision making and drive efficiency.
• Demonstrated ability to work effectively across matrixed organizations and influence without authority.