Senior Software Engineer in Test (Hybrid, 3 Days in Palo Alto Office)

Company Description

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary tests, vast data sets and advanced analytics. The Guardant Health oncology platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has commercially launched Guardant360®, Guardant360 CDx, Guardant360 TissueNext™, Guardant360 Response™, and GuardantOMNI® tests for advanced stage cancer patients, and Guardant Reveal™ for early-stage cancer patients. The Guardant Health screening portfolio, including the Shield™ test, aims to address the needs of individuals eligible for cancer screening.

Guardant Health has been recognized as one of the Best Places to Work in IT for 2025 by Computerworld!

Job Description

Guardant Health seeks an energetic and passionate Senior Software Quality Engineer to join its Software Engineering team. This team is responsible for delivering the product functionality needed to support the laboratory workflow for several of its market leading cancer diagnostic tests as well as integration with various oncology systems.

An ideal candidate would have experience working in a regulated environment with a thorough knowledge of quality engineering best practices and technical expertise to deliver software products that meet business needs in an efficient and fast-paced environment. This role requires someone adept at understanding system architecture, design, and implementation to succinctly develop tailored test strategies and deliver quality software products meeting regulatory standards. The candidate should be apt to work on parallel projects with overlapping schedules, quickly learn new technologies, and demonstrate teamwork and technical leadership.

Essential Duties and Responsibilities:

• Design and execute test coverage for various functional and integration aspects of the Enterprise Lab Information Management System (LabVantage).
• Apply appropriate test methodologies, including but not limited to writing test plans and test cases and executing test scripts within the sprint schedule.
• Create automated test cases and execute them to support scheduled releases.
• Troubleshoot issues identified during testing and report defects; able to distinguish between user error and application anomalies.
• Perform System Integration and performance testing before product releases.
• Provide clear and concise feedback on defects, usability, and other test findings/results.
• Contribute to the continuous improvement of QA processes and methodologies.
• Collaborate with cross-functional teams to ensure timely and robust testing execution as part of a regular release schedule.
• Provide coaching to other team members for designing test strategies and test cases.
• Execute complex testing scenarios, perform in-depth statistical analysis, and interpret results independently.
• Apply QE standards, best practices, and principles to develop quality plans that deliver optimal outcomes across multiple products.
• Deliver test documentation to support software development for medical devices in compliance with FDA, IVDR, CE mark, IEC 62304, PMDA, and ISO 13485 standards.
• Stay updated on industry best practices and emerging technologies relevant to software quality assurance in life sciences.

Qualifications

• B.S. or higher degree in Computer Science, Engineering, Bioinformatics, or a related study or equivalent project experience.
• 8+ years of hands-on testing experience in Service Oriented Architecture environment using COTS/SaaS solutions with API led integrations.
• Solid experience in programming languages like Java, Python
• 5+ years of experience in testing integrations in a hybrid environment leveraging XML/JSON/HL7 message formats.
• 5+ years of experience using databases like Postgres, Oracle, MSSQL Server or Mongo DB.
• 5+ years of experience in test preparation activities within an Agile Development Process – Test Design, Test scripting, Test Data creation.
• 5+ years of API test tools like Postman, Fiddler, RestAssured, SOAPUI, JMeter required.
• Develop test automation scripts to support CI/CD pipeline for software delivery.
• Proven ability to adapt to new technologies and design test strategies.
• Extensive experience in good testing practices, QA methodologies, tools, and processes.
• Excellent communication, presentation, and analytical skills, including strong ability to identify and solve ambigu