Data Engineering Co-op, Empress Therapeutics

Who are we?

Flagship Pioneering has conceived of and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.

Founded by Flagship Pioneering in 2018, Empress Therapeutics pioneers a new paradigm for small molecule drug discovery based on an untapped source of novel, drug-like molecules already inside the human body. Our proprietary bioplatform leverages the power of evolution, human molecular and genetic data, and artificial intelligence to discover advanced starting points for drugs.  Our approach has the potential to create valuable, easy-to-take, safe, cost-effective medicines to treat a wide range of serious unmet medical needs in a fraction of the time and cost and with a higher probability of success than previously thought possible.  

We are seeking an enthusiastic, detail-oriented, and highly motivated co-op to contribute towards construction of our computational biology platform. The Computational Discovery team at Empress Therapeutics develops novel approaches for discovering small molecule therapeutics from omics-scale biological data. In this role, you will help us design and build the platform that enables these discoveries by identifying and implementing emerging methods needed to process and analyze the biological data. You will work closely with a mentor on the Computational Discovery team to build the data solutions supported by innovative technologies. You will gain the broad exposure to a fast-paced, entrepreneurial start-up environment and first-hand experience in translating computational biology research to the discovery of novel therapeutics. 

 KEY RESPONSIBILITIES: 

• Design, implement, and deploy cloud-based data analysis pipelines using data science, cloud computing and analytics methods. 
• Create automated and reliable data ETL pipelines to process and integrate multi-omics datasets from public and proprietary sources to our digital platform. 
• Identify emerging methods and tools in computational approaches to analyze multi-omic datasets and lead prototyping and implementation when applicable.  
• Lead and collaborate closely with other scientists and research associates. 
• Report results to scientific team and management.  

  KEY REQUIREMENTS:  

• A BS or MS student currently enrolled in an accredited college or university in bioinformatics, computational biology, computer science, or related discipline.   
• Proficiency in Python, R, Unix/Linux OS, and command line environments.  

• Cloud computing experience (AWS ecosystem is preferred) 
• Familiarity with DevOps practices 
• Familiarity with data pipeline architecture 
• Experience with SQL/NoSQL is a plus. 
• Knowledge of CI/CD processes and source control tools such as GitHub is a plus.
• Docker/Containerization experience is preferred.
• Working experience and basic understanding of AI/ML is a plus.
• Strong communication and presentation skills, capable of conveying technical information in a clear and thorough manner. 
• Ability to work independently in a multidisciplinary, fast-paced, entrepreneurial, and results-oriented environment. 

 

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.   Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.