Senior Director, Portfolio and Technology Strategy

 ROLE SUMMARY

The Senior Director, Pilot Development, Portfolio Management, Technology & Regulatory Strategy is accountable for providing strategic, technical, and operational leadership across Bioprocess R&D’s non‑GMP pilot plants, portfolio management, and BRD’s regulatory and technology strategy. This role ensures that robust, scalable, and compliant drug substance processes, programs, and technologies are enabled efficiently from early development through clinical readiness.

The role serves as a single point of accountability for pilot‑scale execution, portfolio alignment, and integration of development technologies that support Pfizer’s biologics, vaccines, and advanced therapeutic modalities. The role is responsible for coordination and oversight of BRD projects, the point of contact to the BTxPS Portfolio group and the interface with the PSPTs.  The lead will oversee BRD project forecasts and provide a single point of contact for a cohesive BRD portfolio perspective to BRD LT. The lead will also work with the lines and coordinate the overall Regulatory strategy for BRD and partner with GCMC as the point of contact.

Additionally, the role is responsible for coordination and oversight of BRD’s Technology Strategy, serving as a point of contact to the Pharm Sci Technology and Innovation line, and interface with the BTxPS Technology Council.  This role will lead development and maintenance of a robust BRD Technology Roadmap for implementing BRD’s technology strategy.  This role will provide a single point of contact for implementation of a cohesive BRD technology strategy in cooperation with BRD LT.

The role is global in scope and is a core member of the Bioprocess R&D Leadership Team, partnering closely with Pharmaceutical Sciences, Pfizer Global Supply, Regulatory, Digital, and external collaborators.

ROLE RESPONSIBILITIES

• Lead portfolio operations across BRD ensuring alignment of development priorities, pilot capacity, resources, timelines, and execution risk across programs.
• Design and implement metric driven portfolio tracking systems to allow rapid and flexible adjustments to resource allocations according to project prioritizations. The Lead will collaborate with BRD clinical MFG and the BRD LT in the scheduling and prioritization of projects in the non-GMP and GMP pilot plants to deliver the portfolio.
• Serve as the primary contact to BTxPS Portfolio group, ensuring that information on new projects and technologies and changes to on-going projects is transferred into BRD in a timely manner.  Work with ARD and PhRD portfolio groups to coordinate project initiations at PICM/PPMT and overall project progression through periodic touchpoints
• Work with the BRD LT to manage new BRD rep assignments; triage project issues for prioritization of BRD LT resources on key issues; facilitate forum for strategic input from BRD LT on portfolio
• Provide a mature and experienced perspective on portfolio tracking, project issues, and prioritization to ensure robust oversight and communication of project milestones, deliverables and issues.
• Provide strategic and technical leadership for non‑GMP pilot plants, enabling effective scale‑up, process characterization, and delivery of drug substance for pre‑clinical and clinical studies. 
• Oversee pilot plant readiness, including equipment strategy, maintenance and turnaround, media and buffer support, and inventory management across sites.
• Provide strategic leadership for BRD technology strategy, ensuring technology choices support portfolio priorities, scalability, regulatory readiness, and future manufacturing translation.
• Define and steward the BRD technology roadmap in partnership with Pfizer Global Supply and Digital, including evaluation and deployment of emerging platforms, automation, analytics, and digital enablers.
• Serve as the primary contact to BTxPS technology council, ensuring alignment, visibility, and follow‑through on BRD technology initiatives by tracking projects proposals, coordinating funding requests and investment decisions through the PSTC
• Develop and implement work plans and strategies in response to new BRD technology initiatives, and mentor BRD staff in pursuit of BRD’s technology strategy.
• Serve as a point of contact with PGS for BRD initiatives relating to new technologies, technology transfer, and business practices.
• Oversee BRD legal agreements, external partnerships, and sponsorships by coordinating execution and tracking NDAs, CDAs, MTAs, and collab