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Sr. Engagement Manager, Real World Solutions

OneOncology
United States, United States, United StatesRemotefull_timeVerifiedPosted 19 Feb 2026

About the role

OneOncology is positioning community oncologists to drive the future of cancer care through a patient-centric, physician-driven, and technology-powered model to help improve the lives of everyone living with cancer. Our team is bringing together leaders to the market place to help drive OneOncology’s mission and vision.

Why join us? This is an exciting time to join OneOncology. Our values-driven culture reflects our startup enthusiasm supported by industry leaders in oncology, technology, and finance. We are looking for talented and highly-motivated individuals who demonstrate a natural desire to improve and build new processes that support the meaningful work of community oncologists and the patients they serve.

Job Description:

As a Sr. Engagement Manager, Real World Solutions, you will play a critical role in advancing OneOncology’s Real-World Evidence (RWE) and Real-World Data (RWD) capabilities. You will lead end-to-end RWE/RWD engagements leveraging robust EHR data across OneOncology-partner practices to generate actionable clinical and commercial insights for pharmaceutical stakeholders. In this highly consultative role, you will serve as the primary client lead and trusted advisor, partnering directly with pharmaceutical customers and cross-functional internal teams to scope, execute, and deliver high-impact evidence-generation initiatives that address strategic business questions. 

 

The ideal candidate brings strong analytical expertise, oncology domain knowledge, and the ability to integrate clinical, data science, and business perspectives into clear, actionable recommendations. Success in this role requires strong written and verbal communication skills, strategic thinking, and a collaborative, customer-focused approach. This position reports to the VP of Life Sciences Data Strategy and supports the continued growth and expansion of Real-World Solutions within OneOncology. 

Responsibilities: 

  • Develop a comprehensive understanding of OneOncology’s real-world data assets, analytical capabilities, and pharmaceutical service offerings, as well as the broader oncology treatment landscape, including standards of care, emerging therapies, clinical guidelines, and competitive dynamics across tumor types. 

  • Lead end-to-end RWE/RWD engagements from initial discovery and feasibility assessment through study design, execution, and final delivery, ensuring methodological rigor, data integrity, and alignment with client objectives. 

  • Serve as the primary client lead and trusted consultative partner, translating business questions into actionable analytic strategies and guiding clients through evidence-generation initiatives that support strategic decision-making. 

  • Oversee pre-sales and scoping activities, including business requirement discovery, feasibility assessments, proposal development, and cross-functional coordination through contracting. 

  • Partner closely with Data & Analytics, Clinical, and cross-functional stakeholders to ensure high-quality execution, scientific excellence, and timely delivery of projects. 

  • Develop and deliver high-impact reports, presentations, and data visualizations that clearly communicate complex findings and actionable insights to pharmaceutical stakeholders. 

  • Support scientific dissemination efforts through development of white papers, abstracts, posters, and manuscripts for peer-reviewed publication and conference presentation. 

  • Contribute to the growth and evolution of Real-World Solutions by enhancing methodologies, supporting new se

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Company

OneOncology

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