Director, Data Science

BillionToOne is a next-generation molecular diagnostics company dedicated to developing powerful and accurate diagnostic tests that are accessible to all. Our innovative QCT molecular counting technology significantly enhances the resolution of disease detection using cell-free DNA by over a thousandfold. This groundbreaking technology is integral to our product offerings, including one of our flagship products, Unity Complete™, the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Leveraging the same molecular counting technology, we've expanded our impact into oncology in 2023 with a pioneering liquid biopsy test, Northstar, that combines treatment selection with monitoring. To date, over 1,000,000 patients have benefited from our innovative and precise diagnostic tests, and our Annual Recurring Revenue (ARR) has grown from $0 to $125 million in the last ~4 years.

BillionToOne has successfully raised close to $400 million in funding, with a notable $130 million Series D round completed in June 2024, resulting in a company valuation of over $1 billion. This funding has come from prestigious global institutional investors, including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. BillionToOne has recently been recognized by Forbes as one of America's Best Startup Employers for 2024, highlighting the company's exceptional work environment and commitment to innovation.

Our team has grown significantly and we now proudly employ over 500 highly skilled individuals. Despite substantial growth, we have successfully maintained the unique culture that has defined BillionToOne from inception, continuing to cultivate a team that is not only diverse and passionate but also innovative. Headquartered in Menlo Park, California, with an additional facility in Union City, California, BillionToOne remains at the forefront of significant advances in molecular diagnostics, evidenced by the recent announcement of clinical outcomes data for its Unity Fetal Risk Screen and new advancements in cancer diagnostics. For more detailed information about BillionToOne and its groundbreaking work, please visit our website at www.billiontoone.com.

BillionToOne is seeking an Associate Director/Director, Data Science to lead and scale our data science function. In this role, you will drive the development of advanced analytical frameworks and machine learning models that enhance our genetic testing products. You will lead a team of data scientists and analysts, partnering cross-functionally with bioinformatics, engineering, product, marketing, and commercial teams to deliver data-driven strategies that fuel innovation and business growth.

This role requires a unique blend of technical expertise, strategic vision, and leadership ability. The ideal candidate has a PhD or Master’s in a relevant field, deep experience with statistical modeling and machine learning, and a proven track record of managing high-performing technical teams in a fast-paced environment.

Key Responsibilities:

• Strategic Leadership: Define and execute the data science roadmap to support BillionToOne’s product development, commercial growth, and operational efficiency.
• Team Development: Build, mentor, and lead a team of data scientists and analysts, fostering a high-performance, collaborative culture.
• Advanced Analytics & Modeling: Develop and implement machine learning models and statistical frameworks to analyze genetic data and drive actionable insights.
• Cross-Functional Collaboration: Partner with bioinformatics, product, engineering, marketing, finance, and operations teams to inform strategic decisions and optimize business outcomes.
• Data Infrastructure & Optimization: Ensure efficient data retrieval, transformation, and integration across diverse sources (SQL, JSON, CSV, etc.), leveraging best practices in data engineering and automation.
• Business Impact & Decision Support: Leverage data to inform key business metrics (revenue, profitability, customer acquisition, lifetime value) and develop models to optimize pricing, customer retention, and operational efficiencies.
• Scalability & Innovation: Drive the adoption of emerging data science methodologies and tools to enhance BillionToOne’s competitive