Scientist I, Multispecifics Engineering

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

The Multispecifics Engineering group at AbbVie is seeking a highly motivated research scientist to join a dynamic team supporting biologics drug discovery and multispecifics engineering. This position will impact projects through the design and production of biopharmaceutical products. The ideal candidate should have strong experience with multispecifics production and characterization. Other desirable skills include experience with antibody engineering, protein expression and purification expertise, and sequence analysis tools. The applicant should be able to analyze, document, and report data. She/he should possess excellent communication skills and be comfortable presenting in group settings. 

Key responsibilities: 

• Maintain mammalian cell lines and optimize conditions 

• Design multispecifics for production 

• Prep DNA, express, and purify multispecific biologics to meet project team needs 

• Help maintain DNA and protein inventory for group 

• Prepare aliquots and plates for various assay and project teams and coordinate handoffs 

• Generate production reports and keep lab notebooks up to date 

• Present data at project team meetings and at internal meetings or conferences 

Qualifications

• BS or MS in biology or related field with 5+ years (BS), or 2+ years (MS) of pharmaceutical and/or relevant experience 

• Experience with bacterial and mammalian cell culture 

• Experience with protein, biologics, fragments, and multi-specifics purification 

• Experience with SEC, HIC, IEX purification utilizing AKTAs 

• Experience with in vitro analytical techniques for protein characterization (e.g. SEC, MS, DSF) 

• Experience with plasmid prep, molecular cloning 

• Excellent oral and written communication skills  

• Excellent organization skills and the ability to execute on multiple projects simultaneously 

• Team player with the ability to operate in a fast-paced multi-disciplinary environment 

• Adapt to rapid changes in project priorities and timelines 

• Competency with software programs, including MS Excel, Powerpoint, Word 

•  

  Preferred Qualifications: 

• Experience operating automation equipment (e.g. Hamilton, AssayMap, Kingfisher) in biologics discovery processes 

• Experience with setup and management of biologics and DNA inventory systems such as Freezerpro 

• CHO expression experience including optimizing conditions and plasmid ratios for multispecifics 

• Experience with ELISA, FACS 

• Expereince with mass spectrometry interpretation for complex biologics 

• Experience with the software programs Geneious, Genedata, PMI, and Unicorn 

• Experience with CRO coordination 

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors  including  geographic location, and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. ​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to  participate in our short-term incentive programs.  Note