Global Medical Affairs Leader COPD Omnichannel Confidence and Advocacy

The Global Medical Affairs Leader (GMAL) reports directly to the Medical Head of Inhaled COPD and plays a vital strategic business role. As an experienced leader in Medical Affairs, this individual is responsible for developing medical and promotional advocacy activities for our COPD products.

The GMAL's influence extends globally across AstraZeneca, participating in the Global Medical Team and the Global CFT team, and collaborating with medical personnel in key markets and regions. The Global Medical Affairs Lead (GMAL) for Breztri/Trixeo will shape and execute the global medical strategy. This role will drive medical confidence and advocacy, support country-level guideline pull-through and GDMT acceleration, lead the Next-Generation Product (NGP) Breztri transition and orchestrate omnichannel and AI-enabled initiatives.

Essential Job Responsibilities:

• Medical Strategy and Leadership: Provide global oversight of medical affairs for Breztri/Trixeo, ensuring strategic alignment with therapeutic priorities, lifecycle management, commercial objectives, and scientific standards.

• Medical Confidence and Advocacy Initiatives: Establish external credibility by disseminating robust evidence, engaging thought leaders, and facilitating scientific dialogue; design and implement advocacy initiatives with key stakeholders to reinforce Breztri’s clinical value proposition.

• Guideline and GDMT Support: Collaborate with country medical teams to support the adoption and execution of guideline-driven initiatives and accelerate GDMT (Guideline-Directed Medical Therapy) implementation; supply scientifically validated resources and frameworks to ensure consistency with local healthcare practices.

• NGP Breztri Transition: Manage cross-regional planning and execution of the NGP transition throughout the EU, while preparing for upcoming launches. Coordinate integrated evidence generation, anticipate label changes as needed, and deliver comprehensive education for healthcare professionals to optimize launch and post-launch impact.

• Global-to-Local Enablement: Develop consistent global medical narratives, educational platforms, and toolkits; mentor and align regional and country medical teams on execution standards and key performance indicators.

• Medical Governance and Compliance: Maintain rigorous scientific integrity, uphold ethical standards, and ensure compliance across medical activities, including both promotional and non-promotional reviews.

• Cross-Functional Collaboration: Work collaboratively with R&D, Commercial, Market Access, Regulatory, Safety, and Digital/Analytics to achieve integrated planning, seamless execution, and continuous improvement informed by market insights.

• Insights and Performance Management: Define measurable goals, create dashboards, and establish learning agendas for priority markets; utilize AI and analytics to generate actionable insights and refine the global medical advocacy approach

Essential for the role:

• Demonstrate in-market or regional medical affairs expertise in Respiratory, translating scientific evidence and market dynamics into actionable medical strategies and advocacy roadmaps tailored to local needs; successfully led advocacy initiatives in a local context.

• Build and maintain effective relationships with key external experts (KEEs), patient advocacy groups, healthcare organizations, payers, and healthcare systems, resulting in collaborative initiatives and improved patient outcomes.

• Demonstrated ability to build internal and external networks across geographies and cultures, developing and implementing confidence and advocacy strategies in a global context.

• Generate and analyze substantial clinical and real-world evidence, including successful leadership of Phase 2, 3, or 4 clinical trials, and driving impactful RWE projects such as world-class registries and label-enhancing data initiatives.

• Cultivate strong working relationships with global thought leaders, key experts, professional societies, and other healthcare organizations, contributing to high-impact collaborations and industry advancement.

• Communicate complex scientific concepts clearly and effectively, delivering impactful presentations and ensuring high-quality, objective data communication.

Desirable for the role:

• Doctoral level degree: MD, PhD, or PharmD

• Expertise in advocacy activities, sustainability and next-generation propellants is desirable

• Relevant experience beyond Medical Affairs (e.g. in a marketing/R&D/Market Access/ CI role) is a nice to have.

• Experience launching new products or ind