Process Development Senior Scientist

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Senior Scientist

What you will do

Let’s do this! Let’s change the world!

The Pre-Pivotal Drug Substance Technologies organization at Amgen develops, characterizes, and supports clinical drug substance manufacturing processes for all early-stage programs in the Amgen portfolio.

This lab-based position is located at our Thousand Oaks, CA site. The successful candidate will be responsible for support of the development, characterization, scale-up and support of upstream and downstream purification processes to enable clinical advancement of Amgen programs.

This role is in an integrated bioprocess development group in which cell culture and purification scientists work together to advance Amgen’s rich, exciting and dynamic pipeline. With Amgen’s biology first approach, the position provides the unique opportunity to work on multiple modalities including antibodies, BiTEs, bispecific molecules, and siRNA therapeutics.

The successful candidate will design and execute experiments at the bench scale, spanning the end-to-end drug substance process, within cell culture and purification operations. The candidate will apply established platform approaches and utilize problem-solving skills to rapidly solve day-to-day experimental challenges. Additionally, the candidate will utilize out-of-the-box thinking to contribute to technology development.

Finally, the candidate will also expand and develop skills within the cell-culture and purification functions, thereby further contributing to the integrated group.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications.

Basic Qualifications:

• Bachelor’s degree and 5 years of Scientific experience OR

• Master’s degree and 3 years of Scientific experience OR

• Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]

Preferred Qualifications:

• PhD’s degree in Chemical Engineering, Biochemical Engineering, Life Sciences, or other relevant sciences with a demonstrated record of excellence.

• Ability to identify, develop and implement solutions to practical problems through application of fundamental scientific and engineering principles, preferably in a process development environment.

• Advanced understanding of cell culture and or purification techniques such as aseptic techniques, bioreactor production, harvest operations, protein chromatography, TFF, filtration, etc.; hands-on experience with cell culture or purification operations needed

• Prior experience with data analytical tools (Excel, Spotfire, etc.) is preferred. Experience with statistical analysis and programming in JMP, R, and/or Python environments is a plus.

• Motivated self-starter with excellent oral and written communication, interpersonal, and organizational skills.

• Team player with the ability to successfully work within a diverse team in a dynamic, cross-functional environment.

• Familiarity with design of experiments and statistical analysis of data desirable.

• As the successful candidate will be working on cross-functional process development teams, including research, manufacturing, engineering support groups, etc.

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

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