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Director, Hepatology/Immunology Portfolio and Pipeline Strategy

GSK
United StatesRemotefull_timeVerifiedPosted 21 Jul 2026

About the role

The Director, Hepatology/Immunology Portfolio and Pipeline Strategy leads U.S. portfolio and pipeline strategy for Hepatology/Immunology medicines, spanning in-line brands and pipeline assets from Phase 2 through launch. The role develops and delivers U.S. market analyses and insights, translates U.S. customer perspectives into clinical and health outcome needs, and establishes U.S.-specific insights and market assumptions that inform clinical development plans, financial valuations, and investment decisions for Hepatology/Immunology medicines.

In addition, the role drives U.S. business growth through a forward-looking portfolio vision — including asset prioritization, resourcing, and long-range strategic planning — while creating and implementing strategies for the existing portfolio in partnership with global counterparts through market-responsive U.S.-specific initiatives. The Director crafts the U.S. insights for Hepatology/Immunology disease states, competitors and specialties, supports U.S. leadership representation at LOC and Global committees, and serves as a single point of accountability and voice of the U.S. customer and commercial interests for Hepatology/Immunology assets at early stage-gates.

Key Responsibilities
1. Portfolio Strategy and Lifecycle Management

  • Create and implement portfolio strategies for Hepatology/Immunology medicines in partnership with global counterparts, as well as U.S.-specific initiatives as needed, taking into account multiple customer specialties, multiple indications — including opportunities for indication expansion and lifecycle extension — and the need for flexible, market-responsive objectives.
  • Create market maps for the current and future Hepatology/Immunology portfolio, considering customer and patient needs, MOA assumptions, method of administration, financial impacts, and the evolving healthcare landscape, working seamlessly with stakeholders in Sales, Insights & Analytics, Finance, Medical, Market Access, and GPS.
  • Identify trends in current Hepatology/Immunology brand performance, key specialty customers, and competitors to shape business insights that inform current strategies and GPS.
  • Lead U.S. portfolio and lifecycle strategy across in-line and pipeline Hepatology/Immunology assets, ensuring alignment with brand strategy, commercial objectives, and medical priorities and informing resource allocation and investment choices.
  • Ensure that insights from in-line brands, customer experience, and external experts are consistently integrated into portfolio decisions — including indication prioritization, sequencing, and lifecycle planning for Hepatology/Immunology medicines.

2. Pipeline Strategy and Product Development

  • Develop and deliver U.S. market analyses and insights for the Hepatology/Immunology pipeline in partnership with the cross-functional New Products team.
  • Translate U.S. customer perspectives (HCPs, patients, payers) into clinical trial and health outcome needs to inform clinical development plans and financial valuations for Hepatology/Immunology assets.
  • Establish and ensure delivery of U.S.-specific insights and market assumptions for each Hepatology/Immunology medicine from Phase 2 through LOC activation, approximately 18–24 months prior to launch.
  • Serve as a single point of accountability, leadership, and voice of the U.S. customer for Hepatology/Immunology assets at early stage-gates.
  • For early-stage Hepatology/Immunology assets, lead disease and product strategies for external stakeholders (HCPs, patients, payers).
  • Identify therapeutic and asset-related customer insights and effectively communicate needs to R&D project teams to ensure payer needs are considered as part of clinical development plans.
  • Deliver asset-level recommendations for Phase 2, 2b, and 3 stage-gate decisions for Hepatology/Immunology assets.
  • Develop and maintain a long-range portfolio vision for Hepatology/Immunology, including asset prioritization, resourcing implications, and strategic planning to support future pipeline opportunities.

3. Insights, Analytics, and Market Understanding

  • Develop and leverage analytic approaches to understand U.S. customer needs in partnership with Insights & Analytics and Forecasting.
  • Provide direction and guidance for market research, competitive intelligence, and quantitative/qualitative analyses for market characterization and customer segmentation.
  • Ensure adequate expert input and review of key commercial assessments of the future Hepatology/Immuno

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GSK

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