Principal Investigator

Position: Principal Investigator

Salary Range: $200 - $285k (DOE)

Location: Baltimore, MD (On-site)

About Pharmaron

Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the US, UK, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services.

We're proud of the impact we make and just last year, we supported 887 discovery projects, 1,100+ CMC programs, and 1,397 clinical trials across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers. To learn more, visit www.pharmaron.com.

 

Job Overview

Pharmaron is seeking an experienced physician to serve as a Principal Investigator within our growing Phase I Clinical Research Unit in Baltimore, Maryland.

This is a unique opportunity for a board-certified physician who is passionate about advancing medicine through clinical research while maintaining a strong focus on participant safety and quality care. Clinical research experience is welcomed but not required. Physicians with backgrounds in Internal Medicine, Family Medicine, Emergency Medicine, or related specialties are encouraged to apply.

As Principal Investigator, you will provide medical leadership for early-phase clinical studies, oversee participant safety, collaborate with sponsors and scientific teams, and help shape the future growth of our clinical research programs.

Key Responsibilities:

Clinical Leadership

• Serve as Principal Investigator or Sub-Investigator for Phase I-III clinical studies
• Provide medical oversight and ensure participant safety throughout study conduct
• Review eligibility, medical histories, adverse events, and safety data
• Conduct physical examinations and medical assessments as required

Study Execution & Scientific Collaboration

• Partner with sponsors and internal teams on protocol review, study design, and implementation
• Support dosing activities and ongoing medical monitoring
• Contribute to study interpretation, reporting, and regulatory submissions
• Provide scientific and medical consultation to project teams and clients

Regulatory & Quality Oversight

• Ensure studies are conducted in compliance with ICH-GCP, FDA regulations, and applicable guidelines
• Maintain protocol integrity and oversight responsibilities as listed on FDA Form 1572
• Support inspections, audits, and regulatory interactions when required

Team Leadership

• Mentor and guide Clinical Research Coordinators, nurses, and study staff
• Promote a culture of participant safety, quality, and operational excellence
• Collaborate closely with Medical, Clinical Operations, Pharmacy, Laboratory, and Business Development teams

What We're Looking For:

Required Qualifications

• MD or DO degree from an accredited medical school
• Board Certification in a recognized specialty
• Active and unrestricted medical license
• Minimum 5 years of clinical practice experience
• Current CPR and ACLS certifications
• Strong understanding of patient care, medical ethics, and clinical decision-making
• Excellent communication and leadership skills

Preferred Qualifications

• Previous clinical research experience as a Principal Investigator, Sub-I