Senior Director/Executive Director, Oligonucleotide Chemistry

Your experience includes…  

• PhD in synthetic organic chemistry or process chemistry, and 12+ years of relevant experience. 
• Deep understanding of modern methods in synthetic chemistry with an emphasis on nucleosides, nucleotides and oligonucleotide synthesis, and purification and analytical characterization as applied to nucleic acid therapeutics. 
• Oligonucleotide manufacturing including CRO and CMO capabilities, familiarity with GMP requirements. 
• Contributions to IND, BLA and regulatory filings 
• Strong organizational leadership skills with a proven track record in setting vision/strategy and managing team execution to achieve key company milestones. 
• Lead efforts to identify emerging trends in the oligonucleotide therapeutics field and maintain awareness of the competitive landscape. 
• Prior experience with long oligos via chemical synthesis or ligation is desirable. 

You are interested in… 

• Developing oligonucleotide chemistry vision, strategy, and tactics including overseeing timelines, resourcing and budget planning.  
• Building a world-class oligonucleotide CMC team/platform, including new lab buildout, to support the Tessera pipeline. 
• Lead external manufacturing of oligo with CMOs to support GLP tox studies and IND submissions. 
• Independently leading both internal team and external CRO partners; identifying, developing, and implementing both existing oligo chemistries and developing next-generation chemistry solutions. 
• Working effectively with a cross-functional and highly collaborative biology, technology, and chemistry team to contribute to the delivery of key organizational goals/milestones. 

About you:  

You are an experienced leader with a proven track record of scientific excellence in the oligonucleotide chemistry space. You have demonstrated success in team leadership/organization, platform building and development of oligo’s including a strong publication and patent record. You have hands on experience driving technologies towards the clinics including knowledge related to IND filing.  

Tessera leaders are empathetic and transparent coaches with a strong sense of integrity. They are committed to the growth and development of their teams, the organization and themselves. 

Leadership Structure:  

All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening.   

This position reports to: Sandeep Nema – Senior Vice President, Technical Development 

Meet our Leadership Team and Board of Directors  

Meet your Talent Partner: 

Narissa Furtado-Cordeiro - Manager, Talent Acquisition  

Company Summary:

Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and