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Sr. Finance Enterprise Partner - Therapeutic Area

Genentech
South San Francisco, United Statesfull_timeVerifiedPosted 17 Apr 2026
💰 $355,600/yr($191,500/yr$355,600/yr)

About the role

The Opportunity

The Sr. Finance Enterprise Partner - Therapeutic Area (Sr. FEP - TA) will serve as a strategic finance business partner to the Squad Lead and become an active voice in decision making within the Squad. This role is responsible for ensuring delivery of financial commitments by enabling data-driven trade-offs across functions, integrating insights from Customer Engagement, commercial, medical affairs, market access, pricing, and gross-to-net elements (rebates, discounts, reserves).

The Sr. FEP - TA is also a key connector to the Global team and partners strongly with PT for managing inventories, with R&D to understand pipeline possibilities and partnership in clinical studies, with HQ to provide transparency in our commercial results and strategies.

In addition, the Sr. FEP - TA will serve as a leader for other FEPs and ensure oversight of performance and delivery of FEP value within the squads. 

The ideal candidate connects financial rigor with operational realities, driving alignment across the business to maximize value, optimize resource allocation, and support sustainable growth. Each Sr. FEP - TA manages directly a P&L of roughly USD 6B in sales.

Key Responsibilities

Strategic Finance & Business Partnership:

  • Partner closely with Commercial, Medical, Market Access, Pricing, and Field Leadership to deliver financial targets.

  • Act as the finance lead for portfolio performance, providing actionable insights to guide strategic decisions.

  • Enable trade-off discussions across initiatives (e.g., promotional spend vs. access investments vs. pricing strategy).

  • Support scenario planning for product lifecycle decisions, launch planning, and market changes.

  • Partners with TA FEPs under their supervision and with the Squad Leads of those TAs to ensure effective communication and support to navigate the challenges of the business.
     

Financial Planning & Analysis (FP&A):

  • Collaborate actively in sales forecasting, defining scenarios with the Squad and providing transparency of assumptions to Finance counterparts (local and global when needed). 

  • Lead budgeting, trade-off discussions and investments priorities for the Therapeutic Area and portfolio under their responsibility and long-range planning for the product portfolio.

  • Monitor performance versus plan and identify risks and opportunities early.

  • Develop driver-based models reflecting volume, price, payer mix, and access dynamics.

  • Translate operational metrics into financial outcomes.

  • Oversee the financial forecasting and Month-end reliability of figures for Squad expenses.
     

Gross-to-Net & Revenue Management:

  • Oversee financial modeling of pricing, contracting, rebates, chargebacks, discounts, and reserves.

  • In-depth understanding of reserves and owning voluntary reserves decision making and scenario mapping conversations with Squads. 

  • Partner with Access and Pricing to evaluate contracting strategies and payer negotiations.

  • Ensure accurate revenue forecasting and reserve adequacy.
     

Cross-Functional Integration:

  • Connect insights across Customer Engagement effectiveness, Commercial programs, Medical initiatives, and Access strategies.

  • Facilitate alignment meetings to ensure coordinated decisions across functions.

  • Serve as the financial “single source of truth” for portfolio performance.

  • Partner with different functions as needed to enable the conversations and allow holistic Squad conversations and prioritization.
     

Decision Support & Trade-Off Analysis:

  • Evaluate ROI of commercial investments and promotional programs.

  • Support prioritization of limited resources across products and initiatives.

  • Provide clear recommendations that balance short-term commitments and long-term value.
     

Governance & Reporting:

  • Oversee executive-level reporting on portfolio performance and risks.

  • Support financial reviews, business cases, and investment approvals.

  • Ensure compliance with financial policies and internal controls.
     

Stakeholder Management:

  • Key Stakeholders: Senior commercial leaders, cross-fu

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Company

Genentech

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