Clinical Scientist Associate Director, Cardiovascular

Career Category

Clinical Development

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Clinical Scientist Associate Director, Cardiovascular

What you will do

In this role, the Clinical Scientist Associate Director supports the design, execution, and oversight of cardiovascular trials and other late-phase global clinical studies. The role contributes to protocol development, study execution, medical monitoring support, and clinical data review, ensuring delivery of high-quality, decision-ready clinical data for regulatory submissions and scientific dissemination.

• Support the design, start-up, and execution of global cardiovascular trials, ensuring adherence to protocol, regulatory requirements, and data integrity standards.
• Contribute to development of clinical protocols, statistical analysis plans, investigator brochures, and regulatory documents, with particular focus on cardiovascular endpoints and safety outcomes.
• Collaborate with cross-functional teams to support endpoint strategy, event adjudication processes, and cardiovascular safety monitoring.
• Participate in development and oversight of endpoint adjudication charters, safety monitoring plans, and Data Monitoring Committee (DMC) interactions.
• Provide clinical input into data management plans, CRF design, and clinical data review, with focus on cardiovascular outcomes endpoints (e.g. MACE, hospitalization events, mortality) and/or cardiac imaging endpoints.
• Conduct ongoing clinical data review and signal detection, supporting identification and resolution of safety and data quality issues across global trial sites.
• Support preparation and interpretation of interim analyses, database lock activities, and top-line data readouts.
• Assist Development Lead and Clinical Scientist Director with medical monitoring activities and oversight of CROs, vendors, and adjudication committees.
• Collaborate with clinical operations, biostatistics, safety, regulatory, and medical affairs teams to ensure successful delivery of cardiovascular outcomes and/or cardiac imaging studies.
• Contribute to clinical study reports, regulatory submissions, scientific publications, and presentations for internal and external stakeholders.
• Identify operational or scientific risks and proactively implement mitigation strategies across cross-functional teams.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 3 years of clinical development experience

OR

Master’s degree and 5 years of clinical development experience

OR

Bachelor’s degree and 7 years of clinical development experience

OR

Associate’s degree and 12 years of clinical development experience

OR

High school diploma / GED and 14 years of clinical development experience

Preferred Qualifications:

• 3 years of pharmaceutical clinical drug development experience, including experience supporting late-stage, global clinical trials.
• Demonstrated experience contributing to clinical trial process improvements within a therapeutic area or study team environment
• Industry or academic experience in cardiovascular medicine and/or cardiovascular outcomes trials; experience in large event-driven studies preferred.
• Strong communication and presentation skills, with the ability to clearly convey scientific concepts and clinical data to cross-functional teams and leadership audiences, both written and oral
• Experience supporting the design, monitoring, and implementation of clinical tria