Senior Scientist, High Throughput Automation
MSDAbout the role
Job Description
The Discovery Analytical Research group within Analytical Enabling Capabilities (Analytical R&D) is seeking a highly motivated and technically focused individual interested in a unique role impacting our Company's pipeline from discovery through development, across multiple modalities (small molecule, large molecule, peptides and vaccines).
Key Responsibilities
Design and conduct high-throughput automated experiments for pre-formulation characterization activities to support drug substance and formulation development.
Create and deploy new automation capabilities to drive continuous improvements for operational efficiency, miniaturization, predictive sciences and machine learning.
Utilize their expertise to tackle scientific challenges related to drug-excipient compatibility, enhancing bio-performance with enabled formulation strategies, and physical/biophysical and chemical/biochemical stability of drug candidates.
Investigate physical/biophysical and chemical/biochemical properties of new drug entities, utilizing automated workflows to define formulation strategies for various drug delivery routes in discovery and development.
Build technical expertise in automation and characterization; participate in cross-functional technical teams and inter-departmental initiatives.
Build a strong network internally and across the external academic community and pharmaceutical industry.
Contribute to a culture of scientific excellence, develop a compliance mindset following safety standards, while utilizing electronic lab notebooks, and collaborate with partners and stakeholders across discovery and development.
Education
Bachelor's degree in Materials Science and Engineering, Chemistry, Chemical Engineering, Mechanical Engineering, Biomedical Engineering, Pharmaceutical Sciences or related discipline and 8 years of relevant experience
Masters in Materials Science and Engineering, Chemistry, Chemical Engineering, Mechanical Engineering, Biomedical Engineering, Pharmaceutical Sciences with a minimum of 5 years relevant industrial experience.
PhD in Materials Science and Engineering, Chemistry, Biochemistry, Biophysics, Chemical Engineering, Mechanical Engineering, Biomedical Engineering, Pharmaceutical Sciences or related discipline with 0-3 years of relevant experience.
Experience | Knowledge | Skills
Required
Experience in programming, executing and troubleshooting automation platforms/robotics (i.e. Tecan, Unchained Labs, Hamilton, Chemspeed, etc.)
Strong academic record including publications in peer reviewed journals and presentations at scientific meetings.
Self-motivated, creative and energetic scientist willing to continually learn and solve complex problems.
Principled written and verbal communications
Preferred
Design of experiments, predicative and data sciences
Experience in liquid chromatography (i.e. reverse phase, SEC, IEX) including method development, trouble shooting and data analysis to interrogate solubility, dissolution, and stability.
Physical/Biophysical analysis (i.e. x-ray powder diffraction, dynamic light scattering, micro-flow imaging, back-membrane imaging particle characterization, differential scanning fluorimetry).
Familiarity with computer programming (Python, Visual Basic, etc.)
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separationpackage, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also
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