Postdoc (all genders) Medicinal Chemistry - Targeted Protein Degradation (full-time/part-time)

 

Work Your Magic with us!  

 

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.  

 

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

 

Your role:

You will be a member of the Medicinal Chemistry and Drug Design (MCDD) department at our main research site in Darmstadt, located in the thriving greater Frankfurt/Main area, Germany.

In this role, you will contribute to one of our collaborations within the targeted protein degradation field. As part of Germany´s Clusters4Future initiative, you will work with different partners in the Proxidrugs consortium, including the groups of Prof. Knapp (Goethe University Frankfurt) and Prof. Hausch (TU Darmstadt), towards discovering E3 ligase binders. Together with the research groups of Prof. Thomä and Prof. Correia at the École Polytechnique Fédérale de Lausanne (EPFL, Switzerland) you will aim at discovering novel molecular glue degraders for difficult-to-drug targets.

You will be designing and synthesizing small molecules, developing structure-activity-relationships, and optimizing molecular properties. You will closely collaborate with the scientists at the EPFL or Proxidrugs consortium and with our medicinal and computational chemists in Darmstadt. You will be mentored by experienced drug discovery scientists and your personal development will be supported by trainings adapted to your professional interests and needs.

 

The position is limited until 31 December 2026.

 

Who you are:

• PhD degree in chemistry and optionally post doc experience. Medicinal chemistry know-how is desired.
• Solid understanding and experience with modern technologies applied to organic synthesis.
• Demonstrated high level of creativity and independence in solving complex scientific problems, bringing in a collaborative & enthusiastic spirit into our dynamic multidisciplinary teams.
• Excellent communication skills, fluent in English (written and spoken).

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!
 
Apply now and become a part of our diverse team!