Position Summary

The Ghanbarpour Laboratory, located in the Department of Biochemistry and Molecular Biophysics at WashU Medicine, is now recruiting for a highly motivated Postdoc.

Our research is dedicated to understanding the molecular mechanisms of ATP-dependent AAA+ proteolytic machines in both bacterial systems and human mitochondria, exploring how these complexes form and achieve substrate specificity through cryo-EM and cryo-ET structural biology, biochemical assays, mass spectrometry, and cellular assays.

This position is for someone with experience in cell biology to elucidate the structure and function of these soluble and membrane-anchored ATP-dependent AAA proteases along with accessory proteins in mitochondria.

As a Postdoctoral Researcher in our lab, you will gain extensive hands-on experience with cryo-EM and cryo-ET sample preparation and analysis, heterogeneity analysis tools, mass spectrometry, biochemistry, membrane biology, and cellular assays. The role encourages collaborative opportunities both within our department and with external groups. Importantly, you will have the chance to dedicate 20% of your time to an independent project, which could potentially develop into a faculty proposal for academic positions. This role is designed for individuals who are highly motivated and considering a future career in academia or the biotech industry. This position is supported by R35GM160328.

Job Description

Primary Duties & Responsibilities:

Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/.

For more information on the lab, please visit https://sites.wustl.edu/ghanbarpour/. 

Trains under the supervision of a faculty mentor including (but not limited to):

• Assists with grant preparation and reporting.
• Prepares and submits papers on research.
• Assists in the design of research experiments.
• Evaluates research findings and assists in the reporting of the results.
• Conscientious discharge of their research responsibilities.
• Maintains conformity with ethical standards in research.
• Maintains compliance with good laboratory practice including the maintenance of adequate research records.
• Engages in open and timely discussion with their mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
• Collegial conduct towards co-trainees, staff members and members of the research group.
• Adherence to all applicable University policies, procedures and regulations. All data, research records and materials and other intellectual property generated in University laboratories remain the property of the University.

Working Conditions:

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range:

Base pay is commensurate with experience.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education:

Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree.

Certifications:

No specific certification is required for this position.

Work Experience:

No specific work experience is required for this position.

Skills:

Not Applicable

Driver's License:

A driver's license is not required for this position.

More About This Job

WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.

Preferred Qualifications

Education:

No additional education beyond what is stated in the Required Qualifications section.

Certifications:

No additional certification beyond what is stated in the Required Qualifications section.

Work Experience:

Postdoc