Postdoctoral Scholar

Description

Case Western Reserve University

Postdoctoral Scholar

Department of Biochemistry

 

 

 

The laboratory of Dr. Mohammad Nazim in the Department of Biochemistry at Case

Western Reserve University School of Medicine is seeking highly motivated postdoctoral

researchers to investigate the regulation of post-transcriptional RNA processing and gene

transcription in the chromatin. Specific projects include, but are not limited to, studying the

mechanisms of pre-mRNA alternative splicing, the functional roles of alternative splice variants of

chromatin regulators in cellular development, and how RNA splicing is disrupted in human

diseases such as neurodevelopmental disorders and cancer. The Nazim Lab employs a variety of

cell culture systems, mouse models, and molecular and genomic approaches to address key

questions in RNA biology, chromatin regulation, and gene transcription, with a focus on

mammalian neuronal development. We are seeking curious and dedicated researchers to join our

highly collaborative and dynamic team. In addition to conducting research, postdoctoral fellows

will have opportunities for career development, presentation of research at national and

international conferences, mentoring students, and engaging in scientific outreach.

 

Responsibilities and Duties:

1. The candidate will employ a combination of cell culture models, mouse models, and a

range of molecular biology and biochemical assays to address questions at the

intersection of RNA processing, chromatin regulation, and gene transcription. The lab aims

to uncover how RNA splicing influences gene regulation in chromatin during cellular and

tissue development, and how misregulation of these processes contributes to human

diseases.

2. The successful candidate will independently plan and execute experiments to achieve

research objectives and will have the opportunity to develop new and independent

research directions that build upon the lab’s expertise in RNA and chromatin biology.

3. The position requires high scientific integrity, strong organizational skills for maintaining

scientific records, respect for others, a collaborative mindset, and a commitment to

learning. The successful candidate will present data in lab meetings, journal clubs,

departmental seminars, and scientific conferences, and will contribute to manuscript

preparation and the generation of preliminary data for grant proposals.

Qualifications

Minimum Qualifications:

• Ph.D., M.D., or M.D./Ph.D. degree in biochemistry, molecular biology, cell biology, or a related field
•  A strong background in molecular biology and/or molecular genetics, experience with in vitro and/or in vivo models, and proficiency in computational biology.
•  Published in internationally recognized peer-reviewed journals.
•  Excellent written and oral communication skills necessary.
•  Must be eligible to work in the United States.

Application Instructions

How to apply:

Interested candidates should submit a current CV, a 1-page cover letter describing current and future research interests, and names and contact information for 3 references

 

  Review of applications will begin on November 13th, 2025.

In compliance with the City of Cleveland’s Pay Transparency Ordinance (effective

October 27, 2025), the annual starting base salary range for this position is $55,000 - $62,652. CWRU considers factors such as (but not limited to) the specific grant funding and the terms of the research grant when extending an offer. Postdocs receive individual and family healthcare benefits, life insurance, and employee assistance.

 

Case Western Reserve University is an equal opportunity employer. All applicants are protected under federal and state laws and university policy from discrimination based on race, color, religion, sex, sexual orientation, gender identity or expression, national or ethnic origin, protected veteran status, disability, age and genetic information.

 

Case Western Reserve University complies with the Americans with Disabilities Act regarding reasonable accommodations for applicants with disabilities Applications requiring a reasonable accommodation for any part of the application and hiring process should contact the CWRU Office of Equity at 216.368.3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.