Senior Medical Director, Medical Affairs - Rare Disease Team Lead

The Senior Medical Director, Medical Affairs Team Lead, is a pivotal and strategic leadership role within Regeneron’s Rare Diseases & Cardio-Metabolic franchise. Reporting to the Vice President of Global Medical Affairs, General Medicine, this individual drives the creation and execution of medical strategies for multiple rare disease assets, ensuring alignment with patient-centric goals and organizational priorities.

As the leader of a cross-functional Medical Impact Team (MIT) operating in a matrixed environment, the incumbent serves as a trusted medical and scientific resource, both internally and externally. This role is highly visible and provides significant opportunities to shape the future of Regeneron’s rare disease portfolio.

As a Senior Medical Director in Medical Affaiors a typical day might look like:

• Lead and manage a team of Medical Affairs professionals supporting the General Medicine – Rare Disease Franchise.
• Develop, oversee, and implement focused medical strategies and tactics for rare disease and cardio-metabolic assets.
• Drive annual medical planning, scientific communications, and publication strategies.
• Serve as a key medical and scientific advisor to global and U.S. medical teams, applying disease expertise and business acumen to meet evolving clinical needs.

Cross-Functional Collaboration

• Lead a multifunctional Medical Impact Team (MIT), ensuring seamless collaboration across research, development, commercial, access & reimbursement, and patient advocacy functions.
• Partner with alliance stakeholders (where applicable) to ensure alignment, consensus building, and efficient decision-making within a matrixed organization.
• Co-lead the creation and implementation of robust Phase IIIb/IV plans to support pipeline development and lifecycle management.

Evidence Generation & Data Dissemination

• Provide hands-on leadership in the generation and dissemination of high-quality clinical and non-clinical data, driving impactful publications and scientific communications.
• Oversee the design, execution, and reporting of clinical trials, ensuring timely delivery of high-quality trial documentation.
• Develop and execute external and internal scientific communication strategies, including presentations and publications.

External Engagement & Advocacy

• Act as a medical expert in interactions with regulatory authorities, key opinion leaders, advisory boards, healthcare practitioners, research groups, payers, and alliance partners.
• Build and maintain strategic partnerships with clinical specialists, societies, collaborative groups, advocacy organizations, and other external stakeholders.
• Represent Regeneron and the franchise at scientific forums, ensuring the company’s values and interests are effectively communicated.

This role might be a fit for you if:

• You hold an advanced degree (MD, DO, PhD, or PharmD) with a strong preference for clinical expertise in Cardiovascular/Metabolics or Rare Diseases.
• You have at least 6 years of relevant industry experience, including leadership in medical affairs and successful product launches.
• You bring demonstrated expertise in evidence generation, clinical research, and cross-functional team leadership within a matrixed environment.
• You have experience with regulatory filings, health authority interactions, and evidence generation in rare diseases and/or cardio-metabolic diseases.
• You possess deep knowledge of compliance and global regulatory requirements.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on th