Principal Scientist--Early Bioprocess Development, Vaccines

Why Patients Need You

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. As a Principal Scientist at Early BioProcess Development (EBPD) of Pfizer Vaccine Research and Development (VRD), you will have an opportunity to fulfill Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. You will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines and vaccine to patients around the world.

What You Will Achieve

This is a laboratory-based position where the individual will directly manage individuals and lead a purification process development team for a range of vaccine antigen modalities, with a focus on subunit proteins. This individual will also be responsible for utilizing appropriate analytical and biophysical techniques to characterize key antigen attributes important to purification optimization.

This role requires a combination of strong scientific expertise, innovative problem-solving, and a deep understanding of purification process development.

How You Will Achieve It

• Develop, optimize, and scale-up recovery/purification processes for isolation of vaccine antigens, including protein subunits, nucleotides etc.

• Utilize biophysical methodologies to assess macromolecule interactions and structural properties.

• Present problems and propose technical solutions in discussions with group members. 

• Plan and prioritize related recovery / purification activities.

• Independently analyze, interpret, and provide conclusion and present experimental data.

• Keep abreast of scientific/ technological development by participating in scientific meetings/ seminars and through regular scientific review. Utilize new technologies and establish those technologies to improve purification / recovery capabilities of process development group.

QUALIFICATIONS

Must Have

• Ph.D. and with 5 to 8 years of work experience in industrial or academic setting is required.

• A strong background in protein biochemistry, biophysics, and separation techniques is essential.

• Hands on experience isolating/purifying proteins (especially un-tagged proteins) is required.

• Experience either directly or matrix-managing a scientific team with demonstrated teal leadership skill.

• Proficiency with FPLC, HPLC, UV-Vis, filtration and relevant scientific software (eg. Unicorn).

• Highly organized, detail-oriented with good communication skills.

• Must be proficient with Word, Excel, PowerPoint and relevant scientific software

Nice-to-Have

• Experience with biophysical tools including fluorescence spectroscopy, Octet, CD, AUC, DSC, DLS etc.

• Experience with protein structure/folding.

• Experience with training entry level scientists.

OTHER JOB DETAILS

• Eligible for Relocation Package

• Eligible for Employee Referral Bonus

  
Work Location Assignment: On Premise

The annual base salary for this position ranges from $102,900.00 to $171,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other val