Research Associate - Open Rank

Overview

POSITION SUMMARY: 

 

The goal of the Thyme lab is to understand and develop treatments for intellectual disability. Experimental responsibilities could include the following techniques: molecular biology (PCR, cloning), biochemistry (protein purification), bacterial directed evolution, zebrafish genome-editing, zebrafish line maintenance, antibody staining, RNA in situ analysis, high-resolution imaging, high-throughput larval behavior, adult behavior, cell culture maintenance, drug screens, and transcriptomics (bulk and single-cell RNA-seq). Current and future projects include a study of genes implicated in Down syndrome, a screen of FDA-approved molecules to find modulators of neurodevelopment, and a molecular tool-building project to improve the throughput of drug discovery in an intact brain. See our funded grants at NIH RePORTER, publications, and thymelab.org for additional information. Responsibilities will include collecting, organizing, and reporting research data under minimal supervision; assisting in the design of experiments; maintaining laboratory supplies and equipment; instructing others in basic laboratory techniques; collecting and summarizing data; monitoring results; reporting unusual outcomes. Candidates qualified for a higher RA level are welcome to apply or reach out directly.

 

Applicants should send their CV, a summary of any previous research, and the name of two references to Dr. Summer Thyme, e-mail: Summer.Thyme@umassmed.edu

 

Under the direction of the Principal Investigator (PI) or designee, the Research Associate provides operational support to the laboratory. The Research Associate will perform research experiments as defined by the PI.

 

This is an open-rank posting (there are 4 levels of Research Associate) - candidates will be hired into the level commensurate with their experience.

Responsibilities

ESSENTIAL FUNCTIONS:

Research Associate I:

• Perform laboratory experiments and may be responsible for a single research project.
• Utilize all software relevant to experiment and equipment used.
• Interpret data, form conclusions and decide on next steps under the direction of the PI or designee.
• Maintain accurate records, may modify protocols with the approval of the PI or designee.
• Review literature, publications and grants relevant to assigned projects.
• Record results according to established lab, sponsor & university protocol
• Assist with performing data analysis and/or mathematical computations.
• Maintain a detailed lab notebook according to lab practice.
• Present findings at lab/group meetings
• Monitor laboratory supply levels and order as noted.
• Prepare and label buffers, media, solutions, etc.
• Assist with and comply with all safety regulation and infection control standards.
• Train on IACUC, IRB, EHS, Radiation safety protocols
• Comply with all applicable state, federal university, and sponsor policies and agreements.
• Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions.
• Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab.
• Perform other duties as required.

 

Research Associate II:

Duties noted above plus:

• May assist with the training of new lab personnel.
• Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab.
• May assist with drafting manuscript sessions.

 

Research Associate III:

Duties noted above plus:

• Perform complex laboratory experiments and may be responsible for one or more independent research projects.
• Perform in-depth data analysis and/or mathematical computations.
• Compile and analyze data and present it in a format suitable for publication according to PI specifications.
• May oversee laboratory supply levels and order as needed; negotiate with suppliers to optimize available resources.
• Monitor laboratory equipment service contracts and monitor maintenance on laboratory equipment.
• May manage general operations of the laboratory, including lab personnel, procedures, and projects.
• May create new protocols and/or modify defined protocols, as necessary, and with the approval of the PI.
• Prioritize and perform several tasks or procedures simultaneously with attention to detail.
• Perform duties and experiments with independence.
• Provide training of new lab personnel.
• May monitor laboratory spending in accordance with budget guidelines provided by