Director, Head of Enterprise PMO

Remote:  US

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

The Head of Enterprise PMO will play a pivotal role in shaping and leading the newly formed centralized Program Management Office (PMO) team at GeneDx. This leader will be responsible for centralizing and building the PMO function from the ground up, ensuring alignment across all strategic initiatives and that programs are closely tied to company goals. This role requires someone with a proven track record of establishing and leading enterprise-level program management, who can navigate complex, cross-functional initiatives and implement effective governance to improve internal efficiencies, roadmap alignment, and resource allocation. 

The ideal candidate will be a visionary leader who can create and elevate the PMO function while being hands-on in driving the successful execution of key programs. This person will balance long-term strategic planning with the immediate need to deliver critical business outcomes, positioning GeneDx for continued growth and success. 

Responsibilities 

• Build and Implement PMO Strategy: Develop and execute a comprehensive PMO strategy that aligns with the company’s strategic objectives and growth plans. Create a robust framework to support the company’s dynamic and evolving needs. 

• Establish and enforce project management Foundations: Set up methodologies, standards, and best practices to ensure consistency and quality across all projects, and alignment of roadmaps company-wide 

• Oversee Project Portfolio: Manage the portfolio of projects and programs, ensuring they are delivered on time, within scope, and within budget. 

• Optimize Resource Allocation: Strategically allocate resources and align capacity planning to support project demands effectively. 

• Liaise with Senior Leadership: Serve as the primary point of contact for enterprise project-related communication with senior leadership and key stakeholders, ensuring transparency and alignment. 

• Implement Tracking and Reporting Mechanisms: Develop and deploy robust tracking and reporting mechanisms (dashboards) to monitor project performance and progress against key performance indicators. 

• Develop and Lead the Team: Lead, mentor, and develop a high-performing team of program managers and support staff, fostering a culture of innovation and continuous improvement. 

• Drive Continuous Improvement: Initiate and drive continuous improvement initiatives to enhance project delivery efficiency and effectiveness, ensuring the PMO evolves with the company’s needs. 

 

Qualifications 

• 12+ years proven experience in leading enterprise-level PMO or similar program management functions within a complex, cross-functional environment 

• Strong background in strategic planning, project management, and organizational alignment 

• Exceptional leadership, communication, and interpersonal skills with the ability to influence and drive change at all levels of the organization 

• Demonstrated ability to manage multiple large-scale cross-functional projects simultaneously, with a focus on delivering results that align with strategic business objectives 

• Bachelor’s Degree in Business, Life Sciences, Engineering or a related field and PMP certification is highly desired 

• Experience in the healthcare, biotech, or genomics industry is a plus 

Pay Transparency, Budgeted Ran