Research Sr. Scientist, Dermatology Drug Discovery

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Job Description

Objective / Purpose:

The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs. We seek a skilled Research Sr. Scientist to join our biology and cross-functional discovery teams and create novel drug candidates.

• Generate and execute preclinical development strategies to support candidate selection and mechanistic characterization, facilitating efficient clinical validation of impactful medicines for patients with inflammatory and autoimmune disorders
• Apply deep scientific expertise in immunology and/or cell biology to creatively mature innovative novel concepts within our team, in matrixed collaboration with other Takeda scientists, and external partners. 
• Drive an inclusive, open, and effective culture in a fast-growing drug discovery group.

Accountabilities:

• Generate data packages supporting candidate selection and asset characterization, leveraging subject matter expertise, technical literature, and awareness of current industry standards.
• Champion scientific integrity and rigor in data analysis, preparation, and interpretation of detailed protocols/SOPs.
• Collaborate productively within a matrixed structure, clearly communicate results, challenges, and impact in presentations and conversations with broad audiences.  Integrate data generated from other disciplines.   
• Critically assess and identify vendors and appropriate contract research organizations to supplement internal nonclinical studies.
• Think independently and creatively about novel therapies for patients suffering from immune driven disorders.

Education & Competencies (Technical and Behavioral):

• PhD degree with 2+ years industry experience, or MS with 8+ years’ experience, or BS with 10+ years’ experience.
• Preferred 6+ years of industry experience
• Proven track record in inflammation research and solving complex biology problems.
• Strong experimental design, troubleshooting, and data analysis skills are required.
• Expertise in cell-based and biochemical assay development and screening technologies is desirable (FP, AlphaLISA, TR-FRET, ELISA and etc)
• Excellent written and verbal communication skills and the ability to work effectively in a highly-matrixed environment
• Experience managing CRO work is a plus
• Experience developing and/or evaluating novel small molecule and biologics
• Keeps up with the latest scientific advancement and literature (e.g. competitive landscape, new technology)

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. 

For Location:

Boston, MA

U.S. Base Salary Range:

$133,000.00 - $209,000.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, cer