Deputy Director Manufacturing Operations

Job Title: Deputy Director Manufacturing Operations

• Location: Pearl River, NY

About the Job

Sanofi is seeking an experienced and driven Deputy Director of Manufacturing Operations to lead upstream and downstream manufacturing operations for the production of Flublok drug substance. This leadership role is responsible for managing three manufacturing teams and ensuring all areas are consistently ready for manufacturing operations in full compliance with regulatory and quality standards.

The Deputy Director will serve as a key operational leader, driving a culture of continuous improvement, operational excellence, and accountability across their teams. This individual must bring a strong command of GMP/GDP requirements, Lean manufacturing principles, and people leadership to ensure reliable, high-quality drug substance production in support of Sanofi's mission to improve patient lives.

About Sanofi:

 We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

Main Responsibilities

Leadership & Team Management

• Ensure all areas and employees are safe at all times

• Directly manage three manufacturing teams supporting upstream and downstream Flublok drug substance operations

• Foster a high-performance culture grounded in accountability, collaboration, and continuous improvement

• Provide coaching, mentorship, and professional development to team members at all levels

• Effectively manage conflict within and across teams to maintain a productive and respectful work environment

• Drive a strong sense of urgency in day-to-day operations while maintaining quality and compliance standards

Manufacturing Readiness & Operations

• Ensure manufacturing areas are consistently ready for scheduled production activities

• Oversee upstream and downstream manufacturing processes, including cell culture, protein production, purification, and related unit operations

• Monitor and manage production schedules to meet output targets while maintaining compliance with all applicable standards

• Ensure all equipment, materials, documentation, and personnel are in a state of readiness prior to manufacturing execution

Quality, Compliance & Continuous Improvement

• Ensure all manufacturing activities are conducted in strict accordance with GMP (Good Manufacturing Practice) and GDP (Good Documentation Practice) requirements

• Lead and support deviation investigations, applying structured root cause analysis (RCA) methodologies to identify, document, and resolve manufacturing deviations

• Champion Lean manufacturing principles and defect identification practices to eliminate waste and drive process efficiency

• Implement and sustain performance management routines, including +QDCI (Quality, Delivery, Cost, Involvement) metrics and visual management tools

• Partner with Quality Assurance and Regulatory Affairs to support inspections, audits, and regulatory submissions as needed

Strategic & Cross-Functional Collaboration

• Collaborate with Process Development, Quality, Supply Chain, and Engineering teams to support technology transfers, process improvements, and capacity planning

• Represent manufacturing in cross-functional forums and contribute to site-level strategic initiatives

• Identify and escalate risks to manufacturing readiness, supply continuity, or compliance in a timely manner

• Support the development and management of departmental budgets and resource planning

About You

Basic Qualifications

• Bachelor's degree in Engineering, Science, Life Sciences, Business, or a related field.

• 10+ years of experience in pharmaceutical or biopharmaceutical manufacturing, with 5+ years progressive leadership experience in GMP environment.

• Strong working knowledge of GMP and GDP regulations and their application in a manufacturing environment

• Proven expertise in Lean manufacturing methodologies (5s, Gemba Problem Solving, Daily Capacity Management) and defect identification/reduction

• Demonstrated ability to perform thorough root cause analysis on manufacturing deviations and implement effective corrective actions

• Experience with performance management routines, including +QDCI