Senior Manager, Manufacturing Execution Systems

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Job Description:

Bristol Myers Squibb is seeking a highly skilled and experienced Senior Manager for our Manufacturing Execution Systems (MES) team. The successful candidate will be responsible for leading the MES team, ensuring the effective implementation and maintenance of MES solutions across our manufacturing sites. This role is critical in driving operational excellence, ensuring data integrity, and supporting our mission to deliver innovative medicines to patients. The Senior Manager will manage MES resources and report to the Lead of MES and Enterprise IT applications.

Key Responsibilities:

• Lead the MES team in the design, implementation, and maintenance of MES solutions.

• Collaborate with cross-functional teams including IT, Quality, and Manufacturing to ensure seamless integration of MES with other systems.

• Develop and implement MES strategies that align with the company’s goals and regulatory requirements.

• Ensure data integrity and compliance with industry standards and regulations.

• Provide technical expertise and guidance on MES-related projects and initiatives.

• Manage and mentor a team of MES professionals, fostering a culture of continuous improvement and professional development.

• Oversee the development and execution of MES training programs for end-users.

• Monitor and evaluate the performance of MES systems, identifying areas for improvement and implementing necessary changes.

• Stay current with industry trends and advancements in MES technology to ensure the company remains at the forefront of manufacturing innovation.

• Collaborate with business stakeholders and implementation partner(s) to configure, build, and deploy the MES and other Enterprise IT systems.

• Collaborate with business process leads to design master data, recipes, etc.

• Provide support for operationalizing the manufacturing and peripheral systems.

• Accountable for uninterrupted 24/7 operation of manufacturing systems for CAR-T manufacturing.

• Support daily operation and future enhancements of MES and lower-level systems as Technical System Owner.

Required Competencies, Knowledge, Skills, and Abilities:

• Ability to effectively communicate with both technical and non-technical team members.

• Strong interpersonal skills, especially regarding teamwork and collaboration, client focus, and verbal and written communication.

• Knowledge of industry standard integration protocols and programming applications such as Python, OPC, ODBC, SQL, and Web API.

• Knowledge and experience with MES, preferably Emerson Syncade.

• Knowledge of cGMP, GXP, GAMP, SDLC regulations, including 21CFR part 11, and good documentation practices.

• Knowledge of pharmaceutical, manufacturing, and laboratory systems and equipment that support Biologics and Cell and Gene Therapy manufacturing.

• Strong technical and problem-solving skills and the ability to work independently.

• Demonstrated success working in a high-performing, business results-driven environment.

• Familiarity with Business Intelligence (BI) and reporting programs including InfoBatch, Crystal Reports, Spotfire, Tableau, or similar tool