Principal NPI Engineer- Systems

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Supply Chain Engineering

Job Sub Function:

Process Engineering

Job Category:

Scientific/Technology

All Job Posting Locations:

Danvers, Massachusetts, United States of America

Job Description:

We are searching for the best talent for Principal NPI Engineer-Systems.

Fueled by innovation at the intersection of biology and technology, we’re developing the next generation of smarter, less invasive, more personalized treatments.

Are you passionate about improving and expanding the possibilities of Cardiovascular? Ready to join a team that’s reimagining how we heal? Our Cardiovascular team develops leading solutions for heart recovery, electrophysiology, and stroke. You will join a proud heritage of continually elevating standards of care for stroke, heart failure and atrial fibrillation (AFib) patients.

Your unique talents will help patients on their journey to wellness. Learn more at https://www.jnj.com/medtech

Job Summary

The Principal NPI Engineer – Supplier & Process Engineering (Systems) serves as the senior technical authority for supplier and manufacturing process industrialization across complex new product introduction (NPI) programs. This role sets strategy, defines standards, and leads execution to ensure new products launch with fully capable, scalable, and compliant manufacturing and supplier processes.

The Principal NPI Engineer influences product design architecture, drives cross‑functional alignment, and leads manufacturing readiness, risk management, and supplier capability throughout the product lifecycle. This role operates with high autonomy, exercises seasoned technical judgment, and provides leadership across R&D, Manufacturing, Quality, Regulatory, and Supplier Engineering in a matrixed environment.

Key Responsibilities

New Product Introduction & Manufacturing Readiness

• Lead end‑to‑end NPI execution from early concept through validation and production launch.

• Develop and maintain comprehensive manufacturing readiness frameworks for complex systems with large BOMs (100+ components).

• Drive cross‑functional NPI reviews with R&D, Quality, Supplier Engineering, and Operations to ensure seamless technology transfer and scale‑up.

• Create and execute aggressive NPI project timelines, proactively identifying risks and implementing mitigation strategies.

Manufacturing Process Development & Validation

• Design, implement, validate, and document manufacturing processes, tooling, fixtures, gauges, and equipment (IQ/OQ/PQ).

• Lead development of precision assembly processes for complex electromechanical systems.

• Apply Lean Manufacturing and Six Sigma principles to improve yield, quality, throughput, and cost.

• Lead and participate in continuous improvement initiatives with measurable outcomes.

Design for Manufacturability & Systems Integration

• Partner with R&D to drive DFM/DFA and DFX, ensuring product designs are compatible with manufacturing and supplier capabilities.

• Influence system architecture decisions to reduce risk and improve manufacturability.

• Oversee system integration of mechanical, electrical, instrumentation, and software components into functional systems.

Electromechanical Troubleshooting & Root Cause Analysis

• Lead deep technical investigations to resolve complex manufacturing and build issues.

• Perform hands‑on electromechanical troubleshooting acr