Research Associate - Molecular & cell based assay development

Why work with us?

Our Culture:

At Foghorn Therapeutics, we believe in “People First, Mission Always.”

We put “People First” because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics – demonstrated by our community speaking more than 22 languages and representing over 24 nationalities. We value our teammates as people, not just as employees – validated by our actions that let our people know that we care about them, their families, and their lives.

We say “Mission Always” because we know a relentless commitment to our mission will make a difference in the lives of others. We believe our success will come from evaluating the data to follow the science. We work hard to develop a new class of therapies that could improve the lives of over 2.5 million people with cancer.

Our culture is focused on succeeding through the evaluation of data, not people. And in that, relationships can flourish and develop.

Our Science:

The groundbreaking science behind our therapies continues to yield vital insights into diseases that have confounded physicians and researchers. Our core scientific approach is centered on the chromatin regulatory system, which opens and closes the right sections of DNA at the right time. Breakdowns in the chromatin regulatory system lead to a wide range of diseases, including cancer, impacting millions of people.

Our proprietary Gene Traffic Control® platform is a powerful tool for understanding and modulating the chromatin regulatory system. We are pursuing multiple treatments for breakdowns in this system. We are the only company with the ability to study and target the chromatin regulatory system at scale, in context, and in an integrated way.

About the Role: Research Associate - Molecular & Cell based assay development

Foghorn Therapeutics seeks a motivated Research Associate to join our Oncology biology group. The candidate will play a key role in oncology drug discovery and translational biology research. The successful candidate must have demonstrated proficiency in the development of cell-based assays and use of standard molecular and cellular biology techniques. The candidate should have a track record of applying sound scientific judgment to answer critical questions and a proven ability to design and implement thoughtful and well-controlled experiments. The right candidate will be a driven team player, have excellent interpersonal and communication skills, and be able to balance multiple high-priority tasks in a dynamic environment.

Key Responsibilities

• Independently design, develop and implement a variety of molecular and cellular biology assays to characterize small molecule compounds and determine their mechanism of action.
• Conduct new target biology-related research in disease expansion, resistance mechanisms, and biomarker identification
• Develop cellular readouts of target engagement with small molecules, using literature-derived and internal data sets
• Work collaboratively in a multidisciplinary team, analyze and interpret data, prepare summaries and communicate results to project teams
• Contribute to various aspects of company building, from scientific excellence to enhancing a great company culture

Requirements

Minimum Qualifications and requirements

• A BS degree in Biology or Biochemistry degree

• 1 year + lab experience demonstrating cell culture skills in academic or industry setting
• 1 year + experience with developing or adopting cell-based assays

Preferred Qualifications, skills, role expectations

• 2+ years relevant experience in academia or bio/pharma industry
• MS degree in Biology or Biochemistry degree
• Proven ability to work under limited supervision
• Proven track record for striving for high level of innovation and scientific excellence
• Background in the field of cancer biology and the relevance of oncogenic driver pathways to the development of clinical oncology therapeutics is desirable
• Hands-on experience or expertise with some of the following cellular techniques (Western blot, qPCR, viral vector systems, CRISPR, shRNA, flow cytometry, immunofluorescence, ChIP-seq, ATAC-seq) is strongly preferred
• Flexibility to accommodate changing priorities and deadlines
• Ability to work in a team-based environment
• Excellent verbal and written communication skills

Benefits

Foghorn Therapeutics