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Associate Engineer II, Adjuvant Development and Manufacturing
VaxcyteSan Carlos, United Statesfull_timeVerifiedPosted 27 Jun 2024
💰 $115,000/yr($105,000/yr – $115,000/yr)
About the role
Join our Mission to Protect Humankind!
Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, periodontitis and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.
WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:
*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.
*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.
*MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: Vaxcyte is looking for an energetic and talented individual to play a key supporting role in the Formulation Development function. Vaxcyte is focused on the development of protein conjugate vaccines. This role is searching for an individual who is interested in vaccine research and development and working directly on adjuvant development. This individual’s role would support the adjuvant engineer in large experimentation and execution of adjuvant manufactures. They will be responsible for preparing materials, executing adjuvant development studies, manufacturing of small-scale batches, and characterizing the batches produced to achieve desired results. He/she would also support the broader team (Drug Product) such as analytical and process development groups.
Location: San Carlos, CA Compensation:The compensation package
Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, periodontitis and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.
WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:
*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.
*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.
*MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: Vaxcyte is looking for an energetic and talented individual to play a key supporting role in the Formulation Development function. Vaxcyte is focused on the development of protein conjugate vaccines. This role is searching for an individual who is interested in vaccine research and development and working directly on adjuvant development. This individual’s role would support the adjuvant engineer in large experimentation and execution of adjuvant manufactures. They will be responsible for preparing materials, executing adjuvant development studies, manufacturing of small-scale batches, and characterizing the batches produced to achieve desired results. He/she would also support the broader team (Drug Product) such as analytical and process development groups.
Essential Functions:
- Responsible for preparing reagents/materials (buffers, solutions, etc.), independently manufacturing adjuvants, and performing drug product manufactures.
- Responsible for characterizing batches of adjuvants with analytical validation assays and performing data analysis (Prism, JMP, etc.).
- Experience in problem solving and troubleshooting in a laboratory setting.
- Maintain documentation of experimental execution and results.
- Support the engineer in executing experiments, testing samples, and interpreting data.
- Work with colleagues in ordering lab supplies, new vendor setup, and inventory management of consumable and stability samples.
- This position will report into the Formulation Development and be part of the wider Drug Product group. Significant partnerships with the Analytical and Process Development teams will occur, thus the ability to work within this collaborative environment is essential.
Requirements:
- BS in Pharmaceutical Sciences, Organic/Biochemistry, Chemical/Biochemical Engineering, Biology and a related discipline with 2-5 years of industrial experience or MS in similar field with 0-2 years industry experience.
- Prior knowledge of vaccines, basic chemistry, and nanoparticles highly encourages for this role.
- Experience in particle characterization techniques (Zeta potential, DLS, ELS, etc.) and willing to learn new techniques.
- Strong interpersonal skills, reliable, and able to execute tasks with integrity and excitement.
- Excellent written and verbal communication skills.
- Experience in manufacture of buffers, pipetting, and lab reagents required.
- Experience in Prism, JMP, Benchling and additional laboratory record keeping/data analysis preferred.
- Highly efficient and structured work practices including practical laboratory work, notebook upkeep and general record keeping. Experience in Prism, JMP, ELN (Benchling) and additional laboratory record keeping/data analysis preferred.
- Previous experience working with external vendors preferred but not required.
- Experience with Microsoft Office software (Word, Excel, PowerPoint) is required. An understanding of analytical statistical analysis is also preferred.
- Attention to detail and excellent skills in pipetting and sample preparation.
- Demonstrated ability to work collaboratively in a cross-functional team environment on multiple projects.
Location: San Carlos, CA Compensation:The compensation package
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