Senior Medical Director, Clinical Development

 

Senior Medical Director, Clinical Development

About the Role

We are seeking an accomplished and forward-thinking Senior Medical Director, Clinical Development to lead innovative programs that advance the future of personalized and precision medicine. This high-impact position offers the opportunity to shape clinical strategy, oversee trial design and execution, and collaborate across scientific and clinical teams to improve patient outcomes.

The ideal candidate is a strategic leader who combines scientific depth with operational excellence and a passion for translating data-driven insights into real-world clinical impact.

Key Responsibilities

• Lead the overall strategy, design, and execution of clinical and pre-clinical development programs.

• Develop scientifically rigorous clinical trial protocols and ensure regulatory and ethical compliance.

• Oversee preparation of core materials, including clinical development plans, regulatory submissions, and study documentation.

• Present program strategies and outcomes to internal and external stakeholders, including executive leadership and advisory boards.

• Collaborate with contract research organizations (CROs), academic partners, and cross-functional teams to ensure successful trial delivery.

• Partner with regulatory authorities and scientific collaborators to support study progress and milestone achievement.

• Manage budgets, timelines, and risks to ensure excellence in clinical program execution.

Qualifications

Advanced degree required (PhD, PharmD, or equivalent); MD strongly preferred.

• 10+ years of experience in clinical and/or pre-clinical development within biotechnology or pharmaceutical organizations.

• Proven track record in leading clinical programs and cross-functional teams.

• Expertise in clinical trial design, regulatory strategy, and stakeholder engagement.

• Exceptional communication, organizational, and leadership skills.

 

Preferred Experience

• Background in oncology, immuno-oncology, or precision medicine.

• Experience with biomarker-driven trials and translational research.

• Demonstrated success managing global studies and external partnerships.

 

Why Join Us

This is an exciting opportunity to make a meaningful impact on the future of personalized medicine. You will work with a multidisciplinary team of scientists, clinicians, and innovators committed to advancing clinical research and improving patient outcomes worldwide.

#LI-TH1 #LI-Remote

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$268,600—$340,000 USD

Compensation & Total Rewards 

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of  hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:

• Annual performance incentive bonus

• Long-term equity awards

• Comprehensive health benefits (medical, dental, vision)

• 401(k) with company match

• Generous paid time off and company holidays

• Additional wellness and work-life benefits

Compensation Range $268,600—$335,700 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class inst