Senior Director, Manufacturing Science and Technology

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

PURPOSE AND SCOPE OF POSITION:

This role leads the Manufacturing Science and Technology (MSAT) team of 50+ at the BMS Cell Therapy manufacturing facility in Bothell, WA and will directly report into the Site Head. This role is accountable for the technical support of a multiproduct clinical and commercial GMP autologous CAR-T drug product manufacturing site, including process, facility and equipment validation, manufacturing process support (e.g., investigations, deviations, change controls, CAPAS), automation and MES, plus identifying and implementing policies, procedures and manufacturing strategies to facilitate optimal and compliant production / process and performance.

As a member of the site leadership team, this position will be responsible for helping set strategic direction for the site, including leadership of process improvement activity, capacity increases and introduction of the clinical pipeline into the site to deliver on pivotal and commercial launch responsibilities.  The ideal candidate will have a track record of talent management, nurturing and driving a culture of collaboration, continuous improvement and alignment between various functions and departments on site and across the network, to ensure that major site & business strategic manufacturing objectives are met. In particular the role requires close partnership with Global Technical Operations and the broader BMS community to transfer, implement, validate, file, and license new products/processes and maintain existing products/processes.

This person is a key leader at the site and has significant responsibility for delivering on critical business expectations, including technical transfer and project milestones and managing a department that will have a direct impact on the growth and success of the BMS cell therapy franchise and its impact on our patients.  This role is ideal for a ‘people first’ technical leader, who sees their success through guiding and developing their team to deliver on commitments for the site and broader cell therapy network.  Experience in process development, clinical and commercial manufacturing is preferred due to the nature of the BMS cell therapy portfolio and the site’s responsibility for pivotal clinical and commercial launch activity.

REQUIRED COMPETENCIES:  Knowledge, Skills, and Abilities:

Education:

• Bachelor's Degree required (science or engineering). Graduate or higher-level Degree is preferred.

Experience

• Minimally 15+ years of biotech, cell therapy, pharmaceutical or medical device industry experience in process development, process scale up/manufacturing and process validation.
• 8 or more years ' people management experience
• Experience with commercial scale manufacturing support for mammalian cell culture, aseptic final product filling/kitting/ labeling, liquid media manufacturing (vials, bags, bottles) and/or analytical reagent (e.g. endotoxin detection assay) manufacture, current Good Manufacturing Practices, US/EU regulations, and supervision.
• In depth knowledge of large scale biologic, pharmaceutical or medical device manufacturing, current Good Manufacturing Practices (cGMP) and US/EU regulations and intermediate knowledge of statistical data analysis.
• Knowledge should include a combination of cell biology, cell culture, and aseptic processing technologies and include small scale (laboratory) experience.

DUTIES AND RESPONSIBILITIES:

Leadership & People Management:

• Create an environment of strong team spirit, timely and effective communications, sense of urgency, high motivation and inspire teams to achieve goals in the immediate and longe