Sr. Manager, Business Effectiveness PMO

About Acadia Pharmaceuticals   Acadia is committed to turning scientific promise into meaningful innovation that makes the difference for underserved neurological and rare disease communities around the world. Our commercial portfolio includes the first and only FDA-approved treatments for Parkinson’s disease psychosis and Rett syndrome. We are developing the next wave of therapeutic advancements with a robust and diverse pipeline that includes mid- to late-stage programs in Alzheimer’s disease psychosis and Lewy body dementia psychosis, along with earlier-stage programs that address other underserved patient needs. At Acadia, we’re here to be their difference.

Position Summary:

Sr. Manager, Business Effectiveness PMO plays a key role in driving strategic execution and organizational transformation across Acadia’s Commercial organization. This role leads the planning, coordination, and delivery of complex, cross-functional initiatives that enable business growth and operational excellence.

Acting as a trusted advisor to Commercial leadership, this individual will manage large-scale programs such as organizational redesigns, new product commercialization, and market expansion efforts. The role combines program and project management discipline with change management expertise to ensure initiatives are delivered on time, within budget, and with strong stakeholder adoption.

In addition to strategic program leadership, this role will partner closely with Finance and COBO to manage vendor contracts, quarterly accruals, and budget governance—ensuring accurate forecasting and effective resource allocation across the Commercial portfolio.

The ideal candidate is an organized, proactive problem-solver with deep knowledge of the biopharma commercial model, exceptional communication skills, and the ability to influence across functions and seniority levels.

Primary Responsibilities:

Strategic Program Leadership & Execution

• Demonstrate extensive knowledge of and/or success in professional services or corporate roles, helping Pharma and Life Sciences companies manage project to support growth and execution
• Lead portfolio restructuring programs to allow organizations to drive differentiated growth in the market
• Lead the planning, execution, and closure of major commercial programs, including organizational restructures, new product commercialization readiness, and significant market expansion strategies.
• Define program scope, objectives, governance, resource requirements, and critical success factors in collaboration with Commercial leadership and executive sponsors.
• Develop and maintain detailed program plans, track key milestones, manage interdependencies, and proactively identify and mitigate program risks and issues.

• Ensure programs adhere to defined PMO standards, reporting, and governance structures.

Change Management & Stakeholder Engagement

• Design and execute comprehensive change management strategies and plans (e.g., communications, training, stakeholder analysis, resistance management) that are integrated directly into the program lifecycle.
• Partner with Commercial Leadership and Human Resources to manage the "people side" of changes, ensuring readiness and adoption to maximize return on investment for key initiatives.
• Facilitate senior-level steering committee meetings, ensuring clear communication of program status, risks, and required decisions to maintain alignment and momentum.
• Act as a central point of contact and trusted advisor for stakeholders across Sales, Marketing, and Market Access during periods of significant change.

Contracts & Budget Management

• Partner with Commercial leaders to initiate and manage vendor contracts and related budget
• Partner with COBO leaders, to manage the quarterly accrual process with finance to ensure tracking and spend to forecast goals
• Provide coaching and mentorship on project and change management principles to program teams and functional leaders.
• Ensure rigorous financial oversight of programs, tracking budget adherence and value realization post-implementation.

Education/Experience/Skills:

Bachelor’s degree in business, STEM, or other related field.  An equivalent combination of relevant education and applicable job experience may be considered.  Minimum of 3-5 years of relevant progressive experience in the pharmaceutical/medical device industry with a focus in cross functional leadership experience.  

Must possess:

• Education: Bachelor's degree required